Evidence map›Paper›PMID 38087030›Full record

ArticleScientific reports2023

Rab7 localized on zymogen granules is involved in maturation but not in autophagy or regulated exocytosis in pancreatic acinar cells.

Kenichi Takahashi, Hirosato Mashima, Masanari Sekine, Takeshi Uehara, Takeharu Asano, Ge-Hong Sun-Wada, Yoh Wada, Hirohide Ohnishi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kenichi Takahashi *Department of Gastroenterology, Akita University Graduate School of Medicine, Akita, Japan.
Hirosato Mashima *Department of Gastroenterology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma-Cho, Omiya-Ku, Saitama, 330-8503, Japan. hmashima1-tky@umin.ac.jp.
Masanari SekineDepartment of Gastroenterology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma-Cho, Omiya-Ku, Saitama, 330-8503, Japan.
Takeshi UeharaDepartment of Gastroenterology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma-Cho, Omiya-Ku, Saitama, 330-8503, Japan.
Takeharu AsanoDepartment of Gastroenterology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma-Cho, Omiya-Ku, Saitama, 330-8503, Japan.
Ge-Hong Sun-WadaDepartment of Biochemistry, Faculty of Pharmaceutical Sciences, Doshisha Women's College, Kyoto, Japan.
Yoh WadaDivision of Biological Science, Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Hirohide OhnishiDepartment of Gastroenterology, Jichi Medical University Saitama Medical Center, 1-847 Amanuma-Cho, Omiya-Ku, Saitama, 330-8503, Japan.
Jichi Medical University Saitama Medical Center · JPAkita University · JPDoshisha Women's College of Liberal Arts · JPThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rab7 is known to function in the autophagy and endocytosis pathways in eukaryocytes and is related to various diseases. We recently reported that Rab7 plays a protective role against acute pancreatitis. However, its physiological function in exocytic cells remains unclear. Therefore, we investigated the role of Rab7 in pancreas-specific Rab7 knockout mice (Rab7

Indexed as

Acinar CellsPancreatitisAcute DiseaseAmylasesAnimalsAutophagyExocytosisMiceMice, KnockoutPancreasrab7 GTP-Binding ProteinsSecretory VesiclesAmylasesrab7 GTP-Binding Proteinsrab7 GTP-binding proteins, mouse

Identifiers

PMID38087030
PMCPMC10716180
OpenAlexW4389609250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.