Observational studyJournal of perinatology : official journal of the California Perinatal Association2024
Lung ultrasound score as a tool to predict severity of bronchopulmonary dysplasia in neonates born ≤25 weeks of gestational age.
Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07633184 (Lung Ultrasound Score), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Lung Ultrasound Score (LUS) as Early Predictor of Bronchopulmonary Dysplasia (BPD) in Preterm Newborns: A Prospective, Multicenter, Observational Study
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Characteristics of scores used for quantitative lung ultrasound in neonates: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Diagnostic accuracy of lung ultrasound score for bronchopulmonary dysplasia in preterm neonates: a systematic review and meta-analysis.Frontiers in pediatrics · 2025Pooled it
- The Diagnostic Value of Lung Ultrasound in Bronchopulmonary Dysplasia Among Preterm Infants with Gestational Age ≤ 28 Weeks.Diagnostics (Basel, Switzerland) · 2026Article
- Application of lung ultrasound focusing on posterior zones in prediction of bronchopulmonary dysplasia in preterm infants: a prospective cohort study.Journal of ultrasound · 2026Article
- Accuracy of lung ultrasound in predicting successful extubation in preterm infants born ≤ 25 weeks.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Serial lung ultrasound in predicting the need for surfactant and respiratory course in preterm infants-multicentre observational study (SLURP).European journal of pediatrics · 2025Observational
- Evaluation of the Predictive Value of Lung Ultrasound Scoring Systems in Assessing Bronchopulmonary Dysplasia Severity Among Preterm Infants: Correlation Analysis with Therapeutic Strategies and Clinical Management Protocols.International journal of general medicine · 2025Article
- Proportion of confluent B-Lines predicts respiratory support in term infants shortly after birth.Respiratory research · 2024Observational
- Lung Ultrasound Score in Neonatal RDS: Agreement between Sonography Expert and Neonatologists with Varying Levels of Experience.Healthcare (Basel, Switzerland) · 2024Article
- Diagnostic Accuracy of Lung Ultrasound in Neonatal Diseases: A Systematized Review.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe primary aim was to evaluate whether the addition of the posterior lung aided in diagnostic accuracy of predicting bronchopulmonary dysplasia (BPD) vs moderate-severe BPD (msBPD); the secondary aim was to explore the diagnostic accuracy of two protocols for BPD vs msBPD. STUDY
designThis was a single-center prospective observational study. Preterm infants with a gestational age ≤ 25 weeks were included. Two LUS score protocols were evaluated on the 14th day of life (DOL): (A) evaluating the anterolateral (LUS score-al) lung and (B) the anterolateral combined with posterior (LUS score-alp) lung. The LUS score range for the two protocols was 0-32 and 0-48, respectively.
resultsA total of eighty-nine infants were enrolled. Both the LUS score-al and LUS score-alp were higher in neonates developing BPD and msBPD than in the rest of the cohort (LUS score-al 24 (23,26) vs 22 (20,23); LUS score-alp 36 (34,39) vs 28 (25,32)) (LUS score-al 25 (24,26) vs 23 (21,24); LUS score-alp 40 (39,40) vs 34 (28,36)). The LUS score-al on the 14th DOL showed a moderate diagnostic accuracy to predict BPD and msBPD (AUC 95% CI: 0.797 [0.697-0.896]; 0.811[0.713-0.909]), while the LUS score-alp significantly improved diagnostic accuracy of BPD and msBPD (AUC 95% CI: 0.902 [0.834-0.970]; 0.922 [0.848-0.996]). A cutoff of 25 points in the LUS score-al provided a sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of 76.9%, 79.4%, 3.7, and 0.3 respectively to predict msBPD. Meanwhile, that of 39 points in the LUS score-alp provided a sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of 81%, 98.4%, 50.5 and 0.19 to predict msBPD, respectively.
conclusionsThe LUS score on the 14th DOL can predict BPD and msBPD with moderate diagnostic accuracy. Apart from that, scanning posterior enhanced diagnostic accuracy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.