Evidence map›Paper›PMID 38086904›Full record

ArticleScientific reports2023

AI-based diagnosis of nuclear cataract from slit-lamp videos.

Eisuke Shimizu, Makoto Tanji, Shintato Nakayama, Toshiki Ishikawa, Naomichi Agata, Ryota Yokoiwa, Hiroki Nishimura, Rohan Jeetendra Khemlani, Shinri Sato, Akiko Hanyuda and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  14. Development of the AI Pipeline for Corneal Opacity Detection.Bioengineering (Basel, Switzerland) · 2024
    Article
  15. Applications of Artificial Intelligence in Cataract Surgery: A Review.Clinical ophthalmology (Auckland, N.Z.) · 2024
    Review
  16. Artificial intelligence in the anterior segment of eye diseases.International journal of ophthalmology · 2024
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eisuke ShimizuOUI Inc., Tokyo, Japan. ophthalmolog1st.acek39@keio.jp.
Makoto TanjiOUI Inc., Tokyo, Japan.
Shintato NakayamaOUI Inc., Tokyo, Japan.
Toshiki IshikawaOUI Inc., Tokyo, Japan.
Naomichi AgataOUI Inc., Tokyo, Japan.
Ryota YokoiwaOUI Inc., Tokyo, Japan.
Hiroki NishimuraOUI Inc., Tokyo, Japan.
Rohan Jeetendra KhemlaniOUI Inc., Tokyo, Japan.
Shinri SatoDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Akiko HanyudaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Yasunori SatoDepartment of Preventive Medicine and Public Health, School of Medicine, Keio University, Tokyo, Japan.

Funding

Japan Agency for Medical Research and Development 22hk0102084h0001
6 · The paper itself

Abstract

In ophthalmology, the availability of many fundus photographs and optical coherence tomography images has spurred consideration of using artificial intelligence (AI) for diagnosing retinal and optic nerve disorders. However, AI application for diagnosing anterior segment eye conditions remains unfeasible due to limited standardized images and analysis models. We addressed this limitation by augmenting the quantity of standardized optical images using a video-recordable slit-lamp device. We then investigated whether our proposed machine learning (ML) AI algorithm could accurately diagnose cataracts from videos recorded with this device. We collected 206,574 cataract frames from 1812 cataract eye videos. Ophthalmologists graded the nuclear cataracts (NUCs) using the cataract grading scale of the World Health Organization. These gradings were used to train and validate an ML algorithm. A validation dataset was used to compare the NUC diagnosis and grading of AI and ophthalmologists. The results of individual cataract gradings were: NUC 0: area under the curve (AUC) = 0.967; NUC 1: AUC = 0.928; NUC 2: AUC = 0.923; and NUC 3: AUC = 0.949. Our ML-based cataract diagnostic model achieved performance comparable to a conventional device, presenting a promising and accurate auto diagnostic AI tool.

Indexed as

CataractOptic Nerve DiseasesAlgorithmsArtificial IntelligenceHumans

Identifiers

PMID38086904
PMCPMC10716159

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.