Evidence map›Paper›PMID 38086884›Full record

ArticleNature communications2023

Temperature-related death burden of various neurodegenerative diseases under climate warming: a nationwide modelling study.

Peng Yin, Ya Gao, Renjie Chen, Wei Liu, Cheng He, Junwei Hao, Maigeng Zhou, Haidong Kan

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Extreme heat and hospitalization with Parkinson's disease among older adults.Journal of exposure science & environmental epidemiology · 2026
    Article
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  12. Dementia and Risks of Temperature-Related Mortality and Hospitalizations in Germany.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Bmal1 integrates circadian function and temperature sensing in the suprachiasmatic nucleus.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peng Yin *National Center for Chronic Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Ya Gao *School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, NHC Key Lab of Health Technology Assessment, IRDR ICoE on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health, Fudan University, Shanghai, China.
Renjie Chen *School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, NHC Key Lab of Health Technology Assessment, IRDR ICoE on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health, Fudan University, Shanghai, China.ORCID 0000-0002-9448-0820
Wei LiuNational Center for Chronic Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Cheng HeSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education, NHC Key Lab of Health Technology Assessment, IRDR ICoE on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health, Fudan University, Shanghai, China.ORCID 0000-0002-8470-0834
Junwei HaoDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China. haojunwei@vip.163.com.ORCID 0000-0002-3075-5434
Maigeng ZhouNational Center for Chronic Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. zhoumaigeng@ncncd.chinacdc.cn.ORCID 0000-0001-6402-6347
Haidong KanSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education, NHC Key Lab of Health Technology Assessment, IRDR ICoE on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health, Fudan University, Shanghai, China. kanh@fudan.edu.cn.ORCID 0000-0002-1871-8999

Funding

National Natural Science Foundation of China (National Science Foundation of China) 92043301
6 · The paper itself

Abstract

Limited knowledge exists regarding the ramifications of climate warming on death burden from neurodegenerative diseases. Here, we conducted a nationwide, individual-level, case-crossover study between 2013 and 2019 to investigate the effects of non-optimal temperatures on various neurodegenerative diseases and to predict the potential death burden under different climate change scenarios. Our findings reveal that both low and high temperatures are linked to increased risks of neurodegenerative diseases death. We project that heat-related neurodegenerative disease deaths would increase, while cold-related deaths would decrease. This is characterized by a steeper slope in the high-emission scenario, but a less pronounced trend in the scenarios involving mitigation strategies. Furthermore, we predict that the net changes in attributable death would increase after the mid-21st century, especially under the unrestricted-emission scenario. These results highlight the urgent need for effective climate and public health policies to address the growing challenges of neurodegenerative diseases associated with global warming.

Indexed as

Neurodegenerative DiseasesClimate ChangeCold TemperatureCross-Over StudiesHot TemperatureHumansTemperature

Identifiers

PMID38086884
PMCPMC10716387

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.