Evidence map›Paper›PMID 38086767›Full record

ArticleJournal of the American Society for Mass Spectrometry2024

Selectivity of Explosives Analysis with Ambient Ionization Single Quadrupole Mass Spectrometry: Implications for Trace Detection.

Simone Mathias, Marius Amerio-Cox, Toni Jackson, David Douce, Ashley Sage, Peter Luke, Richard Sleeman, Carol Crean, Patrick Sears

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simone MathiasSchool of Chemistry and Chemical Engineering, University of Surrey, Guildford GU2 7XH, U.K.ORCID 0000-0002-8450-7452
Marius Amerio-CoxSchool of Chemistry and Chemical Engineering, University of Surrey, Guildford GU2 7XH, U.K.
Toni JacksonSchool of Chemistry and Chemical Engineering, University of Surrey, Guildford GU2 7XH, U.K.
David DouceWaters Corporation, Stamford Avenue, Wilmslow SK9 4AX, U.K.
Ashley SageWaters Corporation, Stamford Avenue, Wilmslow SK9 4AX, U.K.
Peter LukeMass Spec Analytical, Future Space UWE North Gate, Bristol BS34 8RB, U.K.
Richard SleemanMass Spec Analytical, Future Space UWE North Gate, Bristol BS34 8RB, U.K.
Carol CreanSchool of Chemistry and Chemical Engineering, University of Surrey, Guildford GU2 7XH, U.K.ORCID 0000-0003-0756-7504
Patrick SearsSchool of Chemistry and Chemical Engineering, University of Surrey, Guildford GU2 7XH, U.K.ORCID 0000-0001-9708-8800

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ambient ionization (AI) is a rapidly growing field in mass spectrometry (MS). It allows for the direct analysis of samples without any sample preparation, making it a promising technique for the detection of explosives. Previous studies have shown that AI can be used to detect a variety of explosives, but the exact gas-phase reactions that occur during ionization are not fully understood. This is further complicated by differences in mass spectrometers and individual experimental set ups between researchers. This study investigated the gas-phase ion reactions of five different explosives using a variety of AI techniques coupled to a Waters QDa mass spectrometer to identify selective ions for explosive detection and identification based on the applied ambient ionization technique. The results showed that the choice of the ion source can have a significant impact on the number of ions observed. This can affect the sensitivity and selectivity of the data produced. The findings of this study provide new insights into the gas-phase ion reactions of explosives and could lead to the development of more sensitive and selective AI-based methods for their detection.

Identifiers

PMID38086767
PMCPMC10767746

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.