Evidence map›Paper›PMID 38086591›Full record

ArticleBMJ open2023

Prevalence of and factors associated with uncontrolled hypertension among patients with early chronic kidney disease attending tertiary hospitals in Dodoma, Tanzania: a cross-sectional study.

Denis D Katatwire, Alfred Meremo

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Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

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0cells of the map it votes in
7citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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7 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Denis D KatatwireDepartment of Internal Medicine, University of Dodoma, Dodoma, Tanzania, United Republic of.
Alfred MeremoDepartment of Internal Medicine, University of Dodoma, Dodoma, Tanzania, United Republic of meremoal@gmail.com.ORCID 0000-0001-5349-7717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the prevalence of uncontrolled hypertension and its associated factors among patients with early chronic kidney disease (CKD) attending medical outpatient clinics at tertiary hospitals in Dodoma, Tanzania.

designCross-sectional study.

settingTwo tertiary hospitals in Dodoma, Tanzania.

participantsThe participants in this study were adult patients (≥18 years) with early CKD stages (1, 2 and 3) who were attending nephrology and medical outpatient clinics from November 2020 to March 2021. Patients who had been attending the clinic for at least 3 months, had baseline clinical data on their files, had estimated glomerular filtration rate (eGFR) ≥30 mL/min/1.73 m OUTCOME MEASURE: The dependent variable was uncontrolled hypertension among patients with early CKD, based on blood pressure measurements.

resultsThe prevalence of hypertension was 58.5% (206 of 352) and the prevalence of uncontrolled hypertension was 58.3% (120 of 206). Among patients with uncontrolled hypertension, 88.3% (106 of 120) had CKD stage 3, 80.2% (96 of 120) reported non-adherence to antihypertensives, 76.7% (92 of 120) were overweight or obese, 72.5% (87 of 120) reported current alcohol use and 26.7% (32 of 120) had diabetes mellitus. Factors that contributed to higher odds of uncontrolled hypertension were: age ≥50 years (OR=5.17, 95 % CI 2.37 to 13.33, p=0.001), alcohol use (OR=11.21, 95% CI 3.83 to 32.84, p=0.001), non-adherence to antihypertensives (OR=10.19, 95% CI 4.22 to 24.61, p=0.001), overweight/obesity (OR=6.28, 95% CI 2.54 to 15.53, p=0.001) and CKD stage 3 (OR=3.52, 95% CI 1.32 to 9.42, p=0.012).

conclusionUncontrolled hypertension was highly prevalent among patients with early CKD in this setting and was associated with age, current alcohol use, non-adherence to antihypertensives, overweight/obesity and declining eGFR.

Indexed as

HypertensionRenal Insufficiency, ChronicAdultAntihypertensive AgentsCross-Sectional StudiesFemaleGlomerular Filtration RateHumansMaleMiddle AgedObesityOverweightPrevalenceRisk FactorsTanzaniaTertiary Care CentersAntihypertensive Agentsadult nephrologyHypertensionnephrology

Identifiers

PMID38086591
PMCPMC10729198

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.