Evidence map›Paper›PMID 38086354›Full record

ArticleAnnals of dermatology2023

Liying Gao, Mi Xie, Xiayu Zhang, Zhenhan Qiu, Zhen Pu, Shan Huang, Bin Li

Open access · diamondAbstract read
In one paragraph

Article in Annals of dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Liying GaoDepartment of Pharmacy, Key Laboratory of Pharmaceutical Research for Metabolic Diseases, Qingdao University of Science and Technology, Qingdao, China.ORCID https://orcid.org/0000-0003-0165-624X
Mi XieDepartment of Pharmacy, Key Laboratory of Pharmaceutical Research for Metabolic Diseases, Qingdao University of Science and Technology, Qingdao, China.ORCID https://orcid.org/0000-0003-4081-0182
Xiayu ZhangDepartment of Pharmacy, Key Laboratory of Pharmaceutical Research for Metabolic Diseases, Qingdao University of Science and Technology, Qingdao, China.ORCID https://orcid.org/0000-0001-8012-1635
Zhenhan QiuDepartment of Pharmacy, Key Laboratory of Pharmaceutical Research for Metabolic Diseases, Qingdao University of Science and Technology, Qingdao, China.ORCID https://orcid.org/0000-0002-8679-0343
Zhen PuCenter of Tibetan Studies (Everest Research Institute), Tibet University, Lhasa, China.ORCID https://orcid.org/0000-0001-5920-353X
Shan HuangDepartment of Pharmacy, Key Laboratory of Pharmaceutical Research for Metabolic Diseases, Qingdao University of Science and Technology, Qingdao, China. huangshan@qust.edu.cn.ORCID https://orcid.org/0000-0001-5345-8398
Bin LiDepartment of Pharmacy, Key Laboratory of Pharmaceutical Research for Metabolic Diseases, Qingdao University of Science and Technology, Qingdao, China. leebin009@163.com.ORCID https://orcid.org/0000-0001-6079-1076
Qingdao University of Science and Technology · CNTibetan Traditional Medical College · CN

Funding

National Natural Science Foundation of China 82074578Shandong Natural Science Foundation Joint Fund ZR2021LZY032
6 · The paper itself

Abstract

backgroundAcne vulgaris (AV) is a common adolescent skin condition which is mainly caused by

objectiveOur previous studies demonstrated that ethanol extracts of

methodsIn the present study, the EMQ treatment potential for AV was evaluated in a

resultsThe results showed that EMQ alleviated edema formation and inflammatory cell infiltration in an acne mouse model by suppressing inflammatory cytokines interleukin (IL)-6, IL-1β, and tumor necrosis factor α expression. Moreover, EMQ inhibited the phosphorylation of MAP kinases (MAPKs) such as p38, JNK, and ERK, the phosphorylation and degradation of IκB-α and the nuclear translocation of nuclear factor kappa B (NF-κB) p65 in LPS-induced RAW264.7 cells.

conclusionThese findings suggest the potent anti-inflammatory activity of EMQ is possibly through the regulation of the MAPKs and NF-κB signaling pathways. Inhibition of

Indexed as

Acne vulgarisMeconopsis quintuplinervia RegelMiceMitogen activated protein kinaseNF-kappa BRAW264.7

Identifiers

PMID38086354
PMCPMC10733074
OpenAlexW4389463803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.