Evidence map›Paper›PMID 38085779›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Antigen exposure reshapes chromatin architecture in central memory CD8

Shaoqi Zhu, Jia Liu, Vanita Patel, Xiuyi Zhao, Weiqun Peng, Hai-Hui Xue

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Exhausted CD8Nature immunology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Antigen exposure reshapes chromatin architecture in central memory CD8Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shaoqi Zhu *Department of Physics, The George Washington University, Washington, DC 20052.ORCID 0000-0001-9509-3526
Jia Liu *Center for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ 07110.
Vanita PatelCenter for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ 07110.
Xiuyi ZhaoCenter for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ 07110.
Weiqun PengDepartment of Physics, The George Washington University, Washington, DC 20052.
Hai-Hui XueCenter for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ 07110.ORCID 0000-0002-9163-7669
Hackensack University Medical Center · USGeorge Washington University · US

Funding

Tcf/Lef-b-catenin in T cell identity and cancerR01AI112579 · NIAID · UNIVERSITY OF IOWA · PI Hai-Hui Xue · 2015 to 2026
$5.4M
Tcf/Lef and B-catenin pathway in follicular helper T cellsR01AI121080 · NIAID · UNIVERSITY OF IOWA · PI Hai-Hui Xue · 2016 to 2026
$4.6M
Ezh2 regulates follicular helper T cell differentiationR01AI139874 · NIAID · UNIVERSITY OF IOWA · PI PENG, WEIQUN, XUE, HAI-HUI · 2018 to 2022
$2.4M
Modulating costimulation pathways to improve follicular helper T cell and antibody responsesI01BX005771 · VA · VA NEW JERSEY HEALTH CARE SYSTEM · PI XUE, HAI-HUI · 2022 to 2025
–
BLRD VA I01 BX005771NIAID NIH HHS R01 AI112579NIAID NIH HHS R01 AI121080NIAID NIH HHS R01 AI139874
6 · The paper itself

Abstract

CD62L

Indexed as

CD8-Positive T-LymphocytesChromatinBinding SitesCCCTC-Binding FactorGenomicsCCCTC-Binding FactorChromatin3D genome organizationcentral memory CD8 T cellschromatin interactionCTCFrecall capacity

Identifiers

PMID38085779
PMCPMC10742382
OpenAlexW4389611001

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.