Evidence map›Paper›PMID 38085774›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Evolution of interfacial mechanics of lung surfactant mimics progression of acute respiratory distress syndrome.

Clara O Ciutara, Steven V Iasella, Boxun Huang, Sourav Barman, Joseph A Zasadzinski

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Mechanistic Insights into Pulmonary Surfactant Inactivation.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  2. Experimental Observations of Graphene at Phospholipid Monolayers.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  3. Review
  4. Article
  5. From relaxation to buckling: A continuum elastic framework connecting surface instabilities of highly compressed lipid thin films.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Mechanical ventilation energy analysis: Recruitment focuses injurious power in the ventilated lung.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Respiratory distress when a lung surfactant loses one of its two hydrophobic tails.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Clara O CiutaraDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0003-4719-7616
Steven V IasellaDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455.
Boxun HuangDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-7822-9695
Sourav BarmanDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-2002-3248
Joseph A ZasadzinskiDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0001-5663-6989
University of Minnesota · US

Funding

LIPID AND PROTEIN EFFECTS ON MONOLAYER STABILITYR01HL051177 · NHLBI · UNIVERSITY OF MINNESOTA · PI Joseph Anthony Zasadzinski · 1994 to 2026
$9.5M
Enhancing Adsorption of Lung Surfactants at the Air-Water Interface Using Methods from Colloid Stability TheoryF32HL151128 · NHLBI · UNIVERSITY OF MINNESOTA · PI IASELLA, STEVEN · 2020 to 2023
$248k
NHLBI NIH HHS F32 HL151128NHLBI NIH HHS R01 HL051177
6 · The paper itself

Abstract

How acute respiratory distress syndrome progresses from underlying disease or trauma is poorly understood, and there are no generally accepted treatments resulting in a 40% mortality rate. However, during the inflammation that accompanies this disease, the phospholipase A

Indexed as

Pulmonary SurfactantsRespiratory Distress SyndromeHumansLungPhospholipases A2Surface-Active AgentsPhospholipases A2Pulmonary SurfactantsSurface-Active Agentsacute respiratory distress syndromedilatational rheologyLaplace instabilitylysolipidsphospholipids

Identifiers

PMID38085774
PMCPMC10743378
OpenAlexW4389611048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.