Evidence map›Paper›PMID 38085559›Full record

ArticleJMIR public health and surveillance2023

Association Between Serum Glycated Hemoglobin Levels at Early Gestation and the Risk of Subsequent Pregnancy Loss in Pregnant Women Without Diabetes Mellitus: Prospective Cohort Study.

Xiaotian Chen, Yi Zhang, Hongyan Chen, Yalan Dou, Yin Wang, Wennan He, Xiaojing Ma, Wei Sheng, Weili Yan, Guoying Huang

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JMIR public health and surveillance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02737644 (Peri-conception Key Nutritional Factors and Primary Prevention of Congenital Heart Disease), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02737644 completednot on this map

Peri-conception Key Nutritional Factors and Primary Prevention of Congenital Heart Disease(CHD)

TypeobservationalSponsorChildren's Hospital of Fudan UniversityRan2016 to 2020Enrolled37,000ConditionsCongenital Heart DiseaseArmsobservation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiaotian ChenDepartment of Clinical Epidemiology & Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0002-0791-5364
Yi ZhangDepartment of Clinical Epidemiology & Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0003-1132-0037
Hongyan ChenDepartment of Clinical Epidemiology & Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0003-2264-3034
Yalan DouDepartment of Clinical Epidemiology & Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0002-4414-4730
Yin WangDepartment of Clinical Epidemiology & Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0002-4491-7465
Wennan HeDepartment of Clinical Epidemiology & Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0002-8292-3997
Xiaojing MaPediatric Heart Center, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0009-0007-6359-0019
Wei ShengShanghai Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai, China.ORCID 0000-0001-7473-0864
Weili Yan *Department of Clinical Epidemiology & Clinical Trial Unit, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0002-7633-7449
Guoying Huang *Pediatric Heart Center, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.ORCID 0000-0003-0505-5839
Children's Hospital of Fudan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs a severe morbidity during pregnancy, the etiology of spontaneous pregnancy loss (SPL) remains largely unknown. Serum glycated hemoglobin (HbA

objectiveThis study aimed to quantify the association between maternal HbA

methodsThis prospective cohort study involved 10,773 pregnant women without diabetes enrolled at their first antenatal care visit at a hospital's early pregnancy clinic from March 2016 to December 2018 in Shanghai, China. HbA

resultsIn total, 273 (2.5%) SPL cases occurred. Every 0.5% increase in HbA

conclusionsHigher HbA

trial registrationClinicalTrials.gov NCT02737644; https://clinicaltrials.gov/study/NCT02737644.

Indexed as

Abortion, SpontaneousDiabetes MellitusChinaFemaleGlycated HemoglobinHumansPregnancyPregnant PeopleProspective StudiesGlycated Hemoglobinadverse outcomeadverse outcomesassociatedassociationassociationscohortdiabetesdiabeticfetalfetal deathfetusgestationalgestational diabetesglycated hemoglobinglycemic controlgynecologicalgynecologyHbA1cHbA1c levelshemoglobin A1cmaternalmetabolic healthmiscarriagemiscarriagesobstetricobstetricspregnancypregnancy losspregnantpregnant womenprospective cohort studyriskrisk ratiorisksspontaneous pregnancy losswomen

Identifiers

PMID38085559
PMCPMC10751628
OpenAlexW4388236105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.