Evidence map›Paper›PMID 38085279›Full record

ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2024

The clinical trajectory of peripheral blood immune cell subsets, T-cell activation, and cytokines in septic patients.

Xuan Lu, Cong-Ying Song, Ping Wang, Li Li, Li-Ying Lin, Shuai Jiang, Jia-Ning Zhou, Meng-Xiao Feng, Yun-Mei Yang, Yuan-Qiang Lu

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Extracellular vesicle-associated PD-L1 induces CD4Cell communication and signaling : CCS · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xuan LuDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Cong-Ying SongDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Ping WangDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Li LiDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Li-Ying LinDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Shuai JiangDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Jia-Ning ZhouDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Meng-Xiao FengDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Yun-Mei YangDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China.
Yuan-Qiang LuDepartment of Geriatric and Emergency Medicine, School of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, 310003, Zhejiang, People's Republic of China. luyuanqiang@zju.edu.cn.
First Affiliated Hospital Zhejiang University · CNZhejiang University · CN

Funding

the Key Research and Development Program of Zhejiang Province 2019C03076
6 · The paper itself

Abstract

OBJECTIVE AND

designChanges in the immune status of patients with sepsis may have a major impact on their prognosis. Our research focused on changes in various immune cell subsets and T-cell activation during the progression of sepsis. METHODS AND SUBJECTS: We collected data from 188 sepsis patients at the First Affiliated Hospital of Zhejiang University School of Medicine. The main focus was on the patient's immunocyte subset typing, T-cell activation/Treg cell analysis, and cytokine assay, which can indicate the immune status of the patient.

resultsThe study found that the number of CD4

conclusionOur study found that immunosuppression occurs in patients early in sepsis. Early monitoring of the patient's immune status may provide a timely warning of the disease.

Indexed as

CytokinesSepsisCD8-Positive T-LymphocytesHumansInterleukin-10Lymphocyte ActivationT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsCytokinesInterleukin-10CytokinesImmunocyteImmunosuppressionSepsisT-cell activation

Identifiers

PMID38085279
OpenAlexW4389623934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.