Evidence map›Paper›PMID 38085270›Full record

ArticleEuropean journal of neurology2024

A strategic neurological research agenda for Europe: Towards clinically relevant and patient-centred neurological research priorities.

Paul Boon, Emma Lescrauwaet, Katina Aleksovska, Maria Konti, Thomas Berger, Matilde Leonardi, Tony Marson, Ulf Kallweit, Elena Moro, Antonio Toscano and 5 more

Abstract read
In one paragraph

Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. European Academy of Neurology: First 10 years.European journal of neurology · 2024
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Paul BoonDepartment of Neurology and 4Brain, Ghent University Hospital, Ghent, Belgium.
Emma LescrauwaetDepartment of Neurology and 4Brain, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0001-6844-5514
Katina AleksovskaEuropean Academy of Neurology, Vienna, Austria.ORCID 0000-0002-2372-4453
Maria KontiEuropean Academy of Neurology, Vienna, Austria.
Thomas BergerDepartment of Neurology and Comprehensive Centre of Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria.
Matilde LeonardiNeurology, Public Health, Disability Unit and Coma Research Centre, Fondazione IRCCS Instituto Neurologico C. Besta, Milan, Italy.
Tony MarsonDepartment of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.
Ulf KallweitCentre for Narcolepsy and Hypersomnolence Disorders, Professorship for Narcolepsy and Hypersomnolence Research, Department of Medicine, Witten/Herdecke University, Witten, Germany.ORCID 0000-0003-1975-6919
Elena MoroDepartment of Psychiatry, Neurology and Neurological Rehabilitation of CHU, Grenoble, France.ORCID 0000-0002-7968-5908
Antonio ToscanoERN-NMD Centre for Neuromuscular Disorders of Messina, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Irena RektorovaBrain and Mind Research, Central European Institute of Technology, Masaryk University, Brno, Czechia.ORCID 0000-0002-5455-4573
Michael CreanEuropean Academy of Neurology, Vienna, Austria.
Anja SanderEuropean Academy of Neurology, Vienna, Austria.
Robert JoyceDiscipline of Occupational Therapy, School of Health Sciences, National University of Ireland, Galway, Ireland.ORCID 0000-0001-5572-0804
Claudio BassettiDepartment of Neurology, Inselspital, University of Bern, Bern, Switzerland.ORCID 0000-0002-4535-0245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeNeurological disorders constitute a significant portion of the global disease burden, affecting >30% of the world's population. This prevalence poses a substantial threat to global health in the foreseeable future. A lack of awareness regarding this high burden of neurological diseases has led to their underrecognition, underappreciation, and insufficient funding. Establishing a strategic and comprehensive research agenda for brain-related studies is a crucial step towards aligning research objectives among all pertinent stakeholders and fostering greater societal awareness.

methodsA scoping literature review was undertaken by a working group from the European Academy of Neurology (EAN) to identify any existing research agendas relevant to neurology. Additionally, a specialized survey was conducted among all EAN scientific panels, including neurologists and patients, inquiring about their perspectives on the current research priorities and gaps in neurology.

resultsThe review revealed the absence of a unified, overarching brain research agenda. Existing research agendas predominantly focus on specialized topics within neurology, resulting in an imbalance in the number of agendas across subspecialties. The survey indicated a prioritization of neurological disorders and research gaps.

conclusionsBuilding upon the findings from the review and survey, key components for a strategic and comprehensive neurological research agenda in Europe were delineated. This research agenda serves as a valuable prioritization tool for neuroscientific researchers, as well as for clinicians, donors, and funding agencies in the field of neurology. It offers essential guidance for creating a roadmap for research and clinical advancement, ultimately leading to heightened awareness and reduced burden of neurological disorders.

Indexed as

Nervous System DiseasesNeurologyEuropeGlobal Burden of DiseaseHumansResearchEuropeneurological disordersresearch agendaresearch gapsresearch priorities

Identifiers

PMID38085270
PMCPMC11235625

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.