Evidence map›Paper›PMID 38085178›Full record

ArticleRheumatology (Oxford, England)2025

The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis.

Jesse Kigozi, Raymond Oppong, Zoe Paskins, Kieran Bromley, Martyn Lewis, Gemma Hughes, Emily Hughes, Susie Hennings, Andrea Cherrington, Alison Hall and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Jesse KigoziHealth Economics Unit, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
Raymond OppongHealth Economics Unit, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.ORCID 0000-0002-0815-4616
Zoe PaskinsSchool of Medicine, Keele University, Keele, UK.ORCID 0000-0002-7783-2986
Kieran BromleyKeele Clinical Trials Unit, Keele University, Keele, UK.
Martyn LewisKeele Clinical Trials Unit, Keele University, Keele, UK.
Gemma HughesKeele Clinical Trials Unit, Keele University, Keele, UK.
Emily HughesKeele Clinical Trials Unit, Keele University, Keele, UK.
Susie HenningsKeele Clinical Trials Unit, Keele University, Keele, UK.
Andrea CherringtonKeele Clinical Trials Unit, Keele University, Keele, UK.
Alison HallSchool of Medicine, Keele University, Keele, UK.
Melanie A HoldenSchool of Medicine, Keele University, Keele, UK.
Kay StevensonHaywood Academic Rheumatology Centre, Midlands Partnership University NHS Foundation Trust, Stoke-on-Trent, UK.
Ajit MenonHaywood Academic Rheumatology Centre, Midlands Partnership University NHS Foundation Trust, Stoke-on-Trent, UK.
Philip RobertsUniversity Hospitals North Midlands, Stoke-on-Trent, UK.
George PeatSchool of Medicine, Keele University, Keele, UK.
Clare JinksSchool of Medicine, Keele University, Keele, UK.
Nadine E FosterSchool of Medicine, Keele University, Keele, UK.
Christian D MallenSchool of Medicine, Keele University, Keele, UK.ORCID 0000-0002-2677-1028
Edward RoddySchool of Medicine, Keele University, Keele, UK.
Keele University · GBMidlands Partnership NHS Foundation Trust · GBNIHR Birmingham Biomedical Research Centre · GBThe University of Queensland · AUUniversity Hospitals of North Midlands NHS Trust · GB

Funding

Applied Research Collaboration West MidlandsDepartment of Health and Social CareNational Institute for Health and Care ResearchNIHR NIHR-RP-2014-04-026Research for Patient Benefit PB PG 0213 30027School for Primary Care Research
6 · The paper itself

Abstract

objectivesEvidence for the comparative cost-effectiveness of intra-articular corticosteroid injection in people with hip osteoarthritis (OA) remains unclear. This study investigated the cost-effectiveness of best current treatment (BCT), comprising advice and education, with BCT plus a single ultrasound-guided intra-articular hip injection of 40 mg triamcinolone acetonide and 4 ml 1% lidocaine hydrochloride (BCT+US-T).

methodsA trial-based cost-utility analysis of BCT+US-T compared with BCT was undertaken over 6 months. Patient-level cost data were obtained, and effectiveness was measured in terms of quality-adjusted life years (QALYs), allowing the calculation of cost per QALY gained from a UK National Health Service (NHS) perspective.

resultsBCT+US-T was associated with lower mean NHS costs (BCT+US-T minus BCT: -£161.6; 95% CI: -£583.95, £54.18) and small but significantly higher mean QALYs than BCT alone over 6 months (BCT+US-T minus BCT: 0.0487; 95% CI: 0.0091, 0.0886). In the base case, BCT+US-T was the most cost-effective and dominated BCT alone. Differences in total costs were driven by number of visits to NHS consultants, private physiotherapists and chiropractors, and hip surgery, which were more common with BCT alone than BCT+US-T.

conclusionIntra-articular corticosteroid injection plus BCT (BCT+US-T) for patients with hip OA results in lower costs and better outcomes, and is highly cost-effective, compared with BCT alone.

trial registrationEudraCT: 2014-003412-37 (8 August 2015) and registered with Current Controlled Trials: ISRCTN 50550256 (28 July 2015). TRIAL PROTOCOL: Full details of the trial protocol can be found in the Supplementary Appendix, available with the full text of this article at https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-018-2153-0, doi: doi.org/10.1186/s12891-018-2153-0.

Indexed as

Anesthetics, LocalCost-Benefit AnalysisOsteoarthritis, HipQuality-Adjusted Life YearsTriamcinolone AcetonideAgedCombined Modality TherapyFemaleGlucocorticoidsHumansInjections, Intra-ArticularLidocaineMaleMiddle AgedPatient Education as TopicTreatment OutcomeAnesthetics, LocalGlucocorticoidsLidocaineTriamcinolone Acetonidecorticosteroid injectioncost-effectivenesscost–utilityeconomic evaluationhip osteoarthritis

Identifiers

PMID38085178
PMCPMC11701301
OpenAlexW4389606948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.