Evidence map›Paper›PMID 38085031›Full record

ArticlemBio2024

An ANI gap within bacterial species that advances the definitions of intra-species units.

Luis M Rodriguez-R, Roth E Conrad, Tomeu Viver, Dorian J Feistel, Blake G Lindner, Stephanus N Venter, Luis H Orellana, Rudolf Amann, Ramon Rossello-Mora, Konstantinos T Konstantinidis

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed.

  1. Trial
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  7. Intraspecific diversity ofMicrobiology spectrum · 2026
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  12. Characterization ofMicrobiology spectrum · 2026
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  14. A novelApplied and environmental microbiology · 2026
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  17. Complete genome sequences of fourMicrobiology resource announcements · 2026
    Article
  18. Article
  19. Article
  20. Article

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luis M Rodriguez-R *Department of Microbiology, and Digital Science Center (DiSC), University of Innsbruck, Innsbruck, Austria.ORCID 0000-0001-7603-3093
Roth E Conrad *School of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0001-8155-8441
Tomeu ViverDepartment of Animal and Microbial Biodiversity, Marine Microbiology Group, Mediterranean Institutes for Advanced Studies (IMEDEA, CSIC-UIB), Esporles, Spain.
Dorian J FeistelSchool of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0001-9478-3170
Blake G LindnerSchool of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Stephanus N VenterDepartment of Biochemistry, Genetics and Microbiology, and Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria, South Africa.
Luis H OrellanaDepartment of Molecular Ecology, Max Planck Institute for Marine Microbiology, Bremen, Germany.
Rudolf AmannDepartment of Molecular Ecology, Max Planck Institute for Marine Microbiology, Bremen, Germany.
Ramon Rossello-MoraDepartment of Animal and Microbial Biodiversity, Marine Microbiology Group, Mediterranean Institutes for Advanced Studies (IMEDEA, CSIC-UIB), Esporles, Spain.
Konstantinos T KonstantinidisSchool of Civil and Environmental Engineering, and School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.ORCID 0000-0002-0954-4755

Funding

National Science Foundation (NSF) 1759831, 2129823
6 · The paper itself

Abstract

importanceBacterial strains and clonal complexes are two cornerstone concepts for microbiology that remain loosely defined, which confuses communication and research. Here we identify a natural gap in genome sequence comparisons among isolate genomes of all well-sequenced species that has gone unnoticed so far and could be used to more accurately and precisely define these and related concepts compared to current methods. These findings advance the molecular toolbox for accurately delineating and following the important units of diversity within prokaryotic species and thus should greatly facilitate future epidemiological and micro-diversity studies across clinical and environmental settings.

Indexed as

BacteriaGenome, BacterialPhylogenyProkaryotic CellsSequence Analysis, DNAANIclonal complexepidemiologymicro-diversitystrain definition

Identifiers

PMID38085031
PMCPMC10790751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.