Evidence map›Paper›PMID 38084960›Full record

ArticleJournal of virology2024

Pemetrexed alleviates piglet diarrhea by blocking the interaction between porcine epidemic diarrhea virus nucleocapsid protein and Ezrin.

Shujuan Zhang, Jing Wang, Xiangyang Liu, Zifei Kan, Yiling Zhang, Zheng Niu, Xia Hu, Li Zhang, Xingcui Zhang, Zhenhui Song

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shujuan Zhang *College of Veterinary Medicine, Southwest University, Chongqing, China.
Jing Wang *College of Veterinary Medicine, Southwest University, Chongqing, China.
Xiangyang Liu *College of Veterinary Medicine, Southwest University, Chongqing, China.
Zifei KanCollege of Veterinary Medicine, Southwest University, Chongqing, China.
Yiling ZhangCollege of Veterinary Medicine, Southwest University, Chongqing, China.
Zheng NiuCollege of Veterinary Medicine, Southwest University, Chongqing, China.ORCID 0000-0002-3855-9286
Xia HuCollege of Veterinary Medicine, Southwest University, Chongqing, China.
Li ZhangCollege of Veterinary Medicine, Southwest University, Chongqing, China.
Xingcui ZhangCollege of Veterinary Medicine, Southwest University, Chongqing, China.ORCID 0009-0003-8551-6910
Zhenhui SongCollege of Veterinary Medicine, Southwest University, Chongqing, China.ORCID 0000-0002-2558-3164
Southwest University · CN

Funding

MOE | Fundamental Research Funds for the Central Universities (Fundamental Research Fund for the Central Universities) XDJK2020RC001Venture and Innovation Support Program for Chongqing Overseas Returnees (Venture & Innovation Support Program for Chongqing Overseas Returnees) cx2019097
6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus that causes high mortality in piglets, thus posing a serious threat to the world pig industry. Porcine epidemic diarrhea (PED) is related to the imbalance of sodium absorption by small intestinal epithelial cells; however, the etiology of sodium imbalanced diarrhea caused by PEDV remains unclear. Herein, we first proved that PEDV can cause a significant decrease in Na

Indexed as

Coronavirus InfectionsPorcine epidemic diarrhea virusSwine DiseasesAnimalsDiarrheaEzrinMolecular Docking SimulationNucleocapsid ProteinsPemetrexedSodiumSodium-Hydrogen Exchanger 3SwineEzrinNucleocapsid ProteinsPemetrexedSodiumSodium-Hydrogen Exchanger 3Ezrinnucleocapsid proteinPemetrexedpiglet diarrheaporcine epidemic diarrhea virus

Identifiers

PMID38084960
PMCPMC10804979
OpenAlexW4389625653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.