ArticleJournal of the American Heart Association2023
One-Year Outcomes According to Mitral Regurgitation Etiology Following Transcatheter Edge-to-Edge Repair With the PASCAL System: Results From a Multicenter Registry.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
3 citing papers in PubMed, 9 citations in OpenAlex.
Philipp von SteinUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine Cologne Germany.ORCID 0000-0003-4548-3897
Christian BeslerDepartment of Cardiology Heart Center Leipzig at University of Leipzig Germany.ORCID 0000-0002-8082-6472
Matthias RiebischDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center University Hospital Essen, Medical Faculty Essen Germany.
Osamah Al-HammadiMedizinische Klinik I, Department of Cardiology University of Giessen Germany.
Tobias RufHeart Valve Center Mainz, Center of Cardiology, Cardiology I University Medical Center Mainz Mainz Germany.ORCID 0000-0003-4540-6621
Muhammed GerçekClinic for General and Interventional Cardiology/Angiology, Heart and Diabetes Centre NRW, Bad Oeynhausen Ruhr University Bochum Bochum Germany.ORCID 0000-0002-1822-936X
Christina GrothusenMedical Clinic I, Department of Cardiology, St.-Johannes-Hospital Dortmund Germany.
Michael MehrMedizinische Klinik und Poliklinik I der Ludwig-Maximilians-Universität München Munich Germany.
Marc Ulrich BecherHeart Center Bonn, Department of Medicine II University Hospital Bonn Bonn Germany.
Kai FriedrichsClinic for General and Interventional Cardiology/Angiology, Heart and Diabetes Centre NRW, Bad Oeynhausen Ruhr University Bochum Bochum Germany.ORCID 0000-0001-9546-3048
Can ÖztürkHeart Center Bonn, Department of Medicine II University Hospital Bonn Bonn Germany.ORCID 0000-0002-5419-2488
Stephan BaldusUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine Cologne Germany.ORCID 0000-0001-8259-1737
Henning GuthoffUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine Cologne Germany.ORCID 0000-0002-0979-1190
Tienush RassafDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center University Hospital Essen, Medical Faculty Essen Germany.
Holger ThieleDepartment of Cardiology Heart Center Leipzig at University of Leipzig Germany.ORCID 0000-0002-0169-998X
Georg NickenigHeart Center Bonn, Department of Medicine II University Hospital Bonn Bonn Germany.
Jörg HausleiterMedizinische Klinik und Poliklinik I der Ludwig-Maximilians-Universität München Munich Germany.ORCID 0000-0003-2909-7961
Helge MöllmannMedical Clinic I, Department of Cardiology, St.-Johannes-Hospital Dortmund Germany.
Patrick HornDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty University Düsseldorf Duesseldorf Germany.
Malte KelmDepartment of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty University Düsseldorf Duesseldorf Germany.ORCID 0000-0003-0060-1052
Volker RudolphClinic for General and Interventional Cardiology/Angiology, Heart and Diabetes Centre NRW, Bad Oeynhausen Ruhr University Bochum Bochum Germany.ORCID 0000-0001-5385-6839
Ralph-Stephan von BardelebenHeart Valve Center Mainz, Center of Cardiology, Cardiology I University Medical Center Mainz Mainz Germany.ORCID 0000-0002-1356-0037
Holger M NefMedizinische Klinik I, Department of Cardiology University of Giessen Germany.
Peter LuedikeDepartment of Cardiology and Vascular Medicine, West German Heart and Vascular Center University Hospital Essen, Medical Faculty Essen Germany.ORCID 0000-0001-7809-2142
Philipp LurzDepartment of Cardiology Heart Center Leipzig at University of Leipzig Germany.ORCID 0000-0002-5993-4487
Roman PfisterUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine Cologne Germany.ORCID 0000-0002-4358-5008
Victor MauriUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine Cologne Germany.ORCID 0000-0003-2678-3501
University of Cologne · DEHeart and Diabetes Center North Rhine-Westphalia · DELeipzig Heart Institute · DEUniversity Hospital Bonn · DEWest German Heart and Vascular Center Essen · DEHeinrich Heine University Düsseldorf · DEJohannes Gutenberg University Mainz · DEJustus-Liebig-Universität Gießen · DELudwig-Maximilians-Universität München · DESt.-Johannes-Hospital Dortmund · DE
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
backgroundWe previously reported procedural and 30-day outcomes of a German early multicenter experience with the PASCAL system for severe mitral regurgitation (MR). This study reports 1-year outcomes of mitral valve transcatheter edge-to-edge repair with the PASCAL system according to MR etiology in a large all-comer cohort. METHODS AND
resultsClinical and echocardiographic outcomes up to 1-year were investigated according to MR etiology (degenerative [DMR], functional [FMR], or mixed [MMR]) in the first 282 patients with symptomatic MR 3+/4+ treated with the PASCAL implant at 9 centers in 2019. A total of 282 patients were included (33% DMR, 50% FMR, 17% MMR). At discharge, MR reduction to ≤1+/2+ was achieved in 58%/87% of DMR, in 75%/97% of FMR, and in 78%/98% of patients with MMR (
conclusionsIn this large all-comer cohort, mitral valve transcatheter edge-to-edge repair with the PASCAL system was associated with an acute and sustained MR reduction at 1-year in all causes. However, in patients with DMR, MR reduction was less pronounced, reflecting the high incidence of complex or very complex anatomies being referred for mitral valve transcatheter edge-to-edge repair.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
One-Year Outcomes According to Mitral Regurgitation Etiology Following Transcatheter Edge-to-Edge Repair With the PASCAL System: Results From a Multicenter Registry. · full record | OpenQuestion