Evidence map›Paper›PMID 38084716›Full record

ArticleJournal of the American Heart Association2023

Hemodynamic Failure Staging With Blood Oxygenation Level-Dependent Cerebrovascular Reactivity and Acetazolamide-Challenged (

Martina Sebök, Frank van der Wouden, Cäcilia Mader, Athina Pangalu, Valerie Treyer, Joseph Arnold Fisher, David John Mikulis, Martin Hüllner, Luca Regli, Jorn Fierstra and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Martina SebökDepartment of Neurosurgery University Hospital Zurich, University of Zurich Switzerland.ORCID 0000-0002-7246-3421
Frank van der WoudenDepartment of Geography University of Hong Kong China.ORCID 0000-0001-9093-3979
Cäcilia MaderDepartment of Nuclear Medicine University Hospital Zurich, University of Zurich Switzerland.
Athina PangaluClinical Neuroscience Center University Hospital Zurich, University of Zurich Switzerland.ORCID 0000-0003-1930-252X
Valerie TreyerDepartment of Nuclear Medicine University Hospital Zurich, University of Zurich Switzerland.ORCID 0000-0002-4584-3031
Joseph Arnold FisherDepartment of Anesthesia and Pain Management University Health Network Toronto Ontario Canada.
David John MikulisInstitute of Medical Science University of Toronto Toronto Ontario Canada.ORCID 0000-0003-3956-0892
Martin HüllnerDepartment of Nuclear Medicine University Hospital Zurich, University of Zurich Switzerland.ORCID 0000-0002-4849-3292
Luca RegliDepartment of Neurosurgery University Hospital Zurich, University of Zurich Switzerland.ORCID 0000-0003-4639-4474
Jorn FierstraDepartment of Neurosurgery University Hospital Zurich, University of Zurich Switzerland.ORCID 0000-0001-6220-0727
Christiaan Hendrik Bas van NiftrikDepartment of Neurosurgery University Hospital Zurich, University of Zurich Switzerland.ORCID 0000-0003-0930-8717
University of Zurich · CHUniversity Health Network · CAUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStaging of hemodynamic failure (HF) in symptomatic patients with cerebrovascular steno-occlusive disease is required to assess the risk of ischemic stroke. Since the gold standard positron emission tomography-based perfusion reserve is unsuitable as a routine clinical imaging tool, blood oxygenation level-dependent cerebrovascular reactivity (BOLD-CVR) with CO METHODS AND

resultsPatients with symptomatic unilateral cerebrovascular steno-occlusive disease, who underwent both an acetazolamide challenge (

conclusionsStandardized and clinically accessible BOLD-CVR examinations harbor sufficient data to provide specific cerebrovascular reactivity cutoff points for HF staging across individual vascular territories in symptomatic patients with unilateral cerebrovascular steno-occlusive disease.

Indexed as

AcetazolamideCerebrovascular DisordersCerebrovascular CirculationHemodynamicsHumansMagnetic Resonance ImagingMiddle Cerebral ArteryPositron-Emission TomographyAcetazolamide(15O‐)H2O‐PETBOLDcerebrovascular reactivityhemodynamic failuresteno‐occlusive diseasesymptomatic stroke

Identifiers

PMID38084716
PMCPMC10863778
OpenAlexW4389616656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.