Evidence map›Paper›PMID 38084439›Full record

ArticleMagnetic resonance in medicine2024

Optimized quantitative mapping of cardiopulmonary oscillations using hyperpolarized

Junlan Lu, Fawaz Alenezi, Elianna Bier, Suphachart Leewiwatwong, David Mummy, Sakib Kabir, Sudarshan Rajagopal, Scott Robertson, Peter J Niedbalski, Bastiaan Driehuys

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. The emerging role of hyperpolarizedExpert review of respiratory medicine · 2025
    Article
  3. Combining hyperpolarizedJournal of applied physiology (Bethesda, Md. : 1985) · 2025
    Article
  4. Mapping the amplitude and phase of dissolvedMagnetic resonance in medicine · 2025
    Article
  5. Article
  6. Article
  7. Functional gas exchange measures onFrontiers in medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Junlan LuMedical Physics Graduate Program, Duke University, Durham, North Carolina, USA.ORCID 0000-0001-5023-7901
Fawaz AleneziDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Elianna BierBiomedical Engineering, Duke University, Durham, North Carolina, USA.
Suphachart LeewiwatwongBiomedical Engineering, Duke University, Durham, North Carolina, USA.
David MummyRadiology, Duke University Medical Center, Durham, North Carolina, USA.ORCID 0000-0001-7885-109X
Sakib KabirRadiology, Duke University Medical Center, Durham, North Carolina, USA.
Sudarshan RajagopalDivision of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Scott RobertsonClinical Imaging Physics Group, Duke University Medical Center, Durham, North Carolina, USA.
Peter J NiedbalskiDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA.ORCID 0000-0002-0528-2508
Bastiaan DriehuysMedical Physics Graduate Program, Duke University, Durham, North Carolina, USA.
Duke University · USDuke Medical Center · USUniversity of Kansas Medical Center · US

Funding

Early Detection of Changes in Pulmonary Gas Exchange by Hyperpolarized Xe MRIR01HL105643 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2011 to 2026
$6.7M
Xenon MRI in Pulmonary HypertensionR01HL153872 · NHLBI · DUKE UNIVERSITY · PI DRIEHUYS, BASTIAAN, RAJAGOPAL, SUDARSHAN K · 2021 to 2024
$2.9M
NHLBI NIH HHS R01 HL105643NHLBI NIH HHS R01 HL153872NIH HHS R01HL105643NIH HHS R01HL12677NIH HHS R01HL153872
6 · The paper itself

Abstract

purposeThe interaction between

methodsA six-zone digital lung phantom was designed to investigate the effects of radial views, key radius, and SNR. One-point Dixon

resultsFor undersampled acquisitions, a key radius of

conclusionsDigital phantom simulations have informed an optimized keyhole reconstruction technique for gas exchange images acquired with standard 1-point Dixon parameters. Our proposed methodology enables more robust quantitative mapping of cardiogenic oscillations, potentially facilitating effective regional quantification of microvascular flow impairment in patients with pulmonary vascular diseases such as CTEPH.

Indexed as

Hypertension, PulmonaryLung DiseasesErythrocytesHumansLungMagnetic Resonance ImagingXenon IsotopesXenon Isotopeshyperpolarized 129Xekeyhole imagingpulmonary microvasculatureradial MRI

Identifiers

PMID38084439
PMCPMC10872359
OpenAlexW4389607475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.