Evidence map›Paper›PMID 38084246›Full record

ArticleJournal of medical biochemistry2023

Reference values and biological determinants for cardiac myosin-binding protein C concentrations assessed with an enzyme-linked immunosorbent assay.

Sylwester M Kloska, Marek Kozinski, Anna Stefanska, Katarzyna Bergmann, Aneta Mankowska-Cyl, Joanna Siodmiak, Grazyna Sypniewska, Magdalena Krintus

Open access · diamondAbstract read
In one paragraph

Article in Journal of medical biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sylwester M KloskaNicolaus Copernicus University, Collegium Medicum, Department of Forensic Medicine, Bydgoszcz, Poland.
Marek KozinskiMedical University of Gda sk, Department of Cardiology and Internal Medicine, Gdynia, Poland.
Anna StefanskaNicolaus Copernicus University, Collegium Medicum, Department of Laboratory Medicine, Bydgoszcz, Poland.
Katarzyna BergmannNicolaus Copernicus University, Collegium Medicum, Department of Laboratory Medicine, Bydgoszcz, Poland.
Aneta Mankowska-CylNicolaus Copernicus University, Collegium Medicum, Department of Laboratory Medicine, Bydgoszcz, Poland.
Joanna SiodmiakNicolaus Copernicus University, Collegium Medicum, Department of Laboratory Medicine, Bydgoszcz, Poland.
Grazyna SypniewskaNicolaus Copernicus University, Collegium Medicum, Department of Laboratory Medicine, Bydgoszcz, Poland.
Magdalena KrintusNicolaus Copernicus University, Collegium Medicum, Department of Laboratory Medicine, Bydgoszcz, Poland.
Nicolaus Copernicus University · PLCollegium Medicum in Bydgoszcz · PLGdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac myosin-binding protein C (cMyC) is a novel cardio-specific biomarker of potential diagnostic and prognostic value for cardiovascular events. This study aims to determine reference values for cMyC and identify biological determinants of its concentration. Methods: A population of 488 presumably healthy adults were enrolled to define biological determinants which affect cMyC concentrations in serum. Concentrations of cMyC were assessed using enzyme-linked immunosorbent assays from commercially available kits. Eligibility for inclusion in this study evaluated all subjects' anthropometric, demographic and laboratory measurements. After applying strict inclusion criteria, a reference population (n=150) was defined and used to determine reference values. Reference values were derived using a robust method.

Indexed as

biomarkercardiac myosin-binding protein CcMyBPCcMyCreference values

Identifiers

PMID38084246
PMCPMC10710818
OpenAlexW4379535833

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.