Evidence map›Paper›PMID 38084130›Full record

ArticleJournal of optical microsystems2023

Characterizing close-focus lenses for microendoscopy.

Dominique Galvez, Zhihan Hong, Andrew D Rocha, John M Heusinkveld, Piaoran Ye, Rongguang Liang, Jennifer K Barton

Abstract read
In one paragraph

Article in Journal of optical microsystems, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dominique GalvezUniversity of Arizona, Wyant College of Optical Sciences, Tucson, United States of America.
Zhihan HongUniversity of Arizona, Wyant College of Optical Sciences, Tucson, United States of America.
Andrew D RochaUniversity of Arizona, Wyant College of Optical Sciences, Tucson, United States of America.
John M HeusinkveldUniversity of Arizona, Department of Obstetrics and Gynecology, Tucson, United States of America.
Piaoran YeUniversity of Arizona, Department of Chemistry & Biochemistry, Tucson, United States of America.
Rongguang LiangUniversity of Arizona, Wyant College of Optical Sciences, Tucson, United States of America.
Jennifer K BartonUniversity of Arizona, Wyant College of Optical Sciences, Tucson, United States of America.

Funding

Ovarian Cancer Detection with Blood- and Imaging-Based BiomarkersR01CA260399 · NCI · UNIVERSITY OF ARIZONA · PI Jennifer Kehlet Barton, David A. Fishman · 2022 to 2026
$3.9M
Development of in vitro diagnostic multivariate index assay using liquid-based cervical cytology specimen and/or serum/plasma biomarkers for the detection of early stage or low-volume ovarian cancerU01CA200469 · NCI · JOHNS HOPKINS UNIVERSITY · PI SHIH, IE-MING, ZHANG, ZHEN · 2016 to 2021
$2.9M
Molecular and Imaging Assessment of Fallopian Tube HealthR21CA229707 · NCI · UNIVERSITY OF ARIZONA · PI BARTON, JENNIFER KEHLET · 2018 to 2019
$385k
3D printing glass micro-objectives for ultrathin endoscopeR21CA268190 · NCI · UNIVERSITY OF ARIZONA · PI LIANG, RONGGUANG · 2022 to 2023
$367k
NCI NIH HHS R01 CA260399NCI NIH HHS R21 CA229707NCI NIH HHS R21 CA268190NCI NIH HHS U01 CA200469
6 · The paper itself

Abstract

Microendoscopes are commonly used in small lumens in the body, for which a focus near to the distal tip and ability to operate in an aqueous environment are paramount for navigation and disease detection. Commercially available distal optic systems below 1mm in diameter are severely limited, and custom micro lenses are generally very expensive. Gradient index of refraction (GRIN) singlets are available in small diameters but have limited optical performance adjustability. Three-dimensional (3D) printed monolithic optical systems are an emerging option that may be suitable for enabling high performance, close-focus imaging. In this manuscript, we compared the optical performance of three custom distal optic systems; a custom-pitch GRIN singlet, 3D-printed monolithic doublet, and 3D-printed monolithic triplet, with a nominal working distance (WD) of 1.5mm, 0.5mm and 0.4mm in 0.9% saline. These short WDs are ideal for microendoscopy in collapsed or flushed lumens such as pancreatic duct or fallopian tube. The GRIN singlet had performance limited only by the fiber bundle relay over 0.9mm to 1.6 mm depth of field (DOF). The 3D printed doublet was able to achieve a comparable DOF of 0.71mm, while the 3D printed triplet suffered the most limited DOF of 0.55mm. 3D printing enables flexible design of monolithic multi-element systems with aspheric surfaces of very short WDs and relative ease of integration.

Indexed as

3D printingEndoscopyLens designmicroendoscopemulti-modal imaging

Identifiers

PMID38084130
PMCPMC10712292

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.