Evidence map›Paper›PMID 38084063›Full record

ArticleJournal of attention disorders2024

Anxiety and Disruptive Behavior Symptoms and Disorders in Preschool-Age Offspring of Parents With and Without Bipolar Disorder: Associations With Parental Comorbidity.

Madelaine R Abel, Aude Henin, Jordan Holmén, Elana Kagan, Antonia Hamilton, Nestor Noyola, Dina R Hirshfeld-Becker

Abstract read
In one paragraph

Article in Journal of attention disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Madelaine R AbelChild Cognitive Behavioral Therapy Program, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-8632-6543
Aude HeninChild Cognitive Behavioral Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
Jordan HolménChild Cognitive Behavioral Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
Elana KaganChild Cognitive Behavioral Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
Antonia HamiltonChild Cognitive Behavioral Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
Nestor NoyolaChild Cognitive Behavioral Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
Dina R Hirshfeld-BeckerChild Cognitive Behavioral Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
Harvard University · USMassachusetts General Hospital · USSt. John's University · US

Funding

Risk Factors for Adverse Outcome in Young Offspring of Bipolar ParentsR01MH076923 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HIRSHFELD-BECKER, DINA R · 2007 to 2011
$3.2M
NIMH NIH HHS R01 MH076923
6 · The paper itself

Abstract

objectiveWe examined the relative contribution of parental bipolar disorder (BPD) and psychiatric comorbidities (disruptive behavior disorders [DBD] and anxiety disorders) in predicting psychiatric symptoms and disorders in 2-5-year-old offspring.

methodsParticipants were 60 families with a parent with BPD and 78 offspring and 70 comparison families in which neither parent had a mood disorder and 91 offspring. Parent and offspring diagnoses and symptoms were assessed using standardized diagnostic interviews and measures, with offspring assessors masked to parental diagnoses.

resultsOffspring of parents with BPD had significant elevations in behavioral, mood and anxiety disorders and symptoms. Both parental BPD and DBD contributed to elevations in child disruptive behavioral symptoms, whereas child anxiety symptoms were more strongly predicted by comorbid parental anxiety. Parental BPD was a stronger predictor than comorbid DBD of child DBDs.

conclusionSome of the elevated risk for disorders in preschoolers is accounted for by parental comorbidity.

Indexed as

Attention Deficit Disorder with HyperactivityBipolar DisorderChild of Impaired ParentsProblem BehaviorAnxietyAnxiety DisordersChildChild, PreschoolComorbidityHumansParentsRisk Factorschild psychopathologyparent bipolar disorderparent psychopathologypreschoolers

Identifiers

PMID38084063
PMCPMC13242798
OpenAlexW4389623050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.