Evidence map›Paper›PMID 38083897›Full record

ReviewCurrent hypertension reviews2024

Hypertension Management in Peripheral Artery Disease: A Mini Review.

A Kharawala, S Nagraj, S Pargaonkar, J Seo, D G Kokkinidis, S E Altin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. SerumDiagnostics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

A KharawalaDepartment of Medicine, New York City Health+Hospitals/Jacobi, Bronx, NY, USA.ORCID 0000-0003-3989-4489
S NagrajAlbert Einstein College of Medicine, Bronx, NY, USA.ORCID 0000-0002-6230-7214
S PargaonkarDepartment of Medicine, New York City Health+Hospitals/Jacobi, Bronx, NY, USA.
J SeoDepartment of Medicine, New York City Health+Hospitals/Jacobi, Bronx, NY, USA.
D G KokkinidisSection of Cardiovascular Medicine, Yale School of Medicine, Yale University, New Haven, CT, USA.
S E AltinSection of Cardiovascular Medicine, Yale School of Medicine, Yale University, New Haven, CT, USA.
Albert Einstein College of Medicine · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lower extremity peripheral artery disease (PAD) affects over 230 million adults globally, with hypertension being one of the major risk factors for the development of PAD. Despite the high prevalence, patients with hypertension who have concomitant PAD are less likely to receive adequate therapy. Through this review, we present the current evidence underlying hypertension management in PAD, guideline-directed therapies, and areas pending further investigation. Multiple studies have shown that both high and relatively lower blood pressure levels are associated with worse health outcomes, including increased morbidity and mortality. Hence, guideline-directed recommendation involves cautious management of hypertensive patients with PAD while ensuring hypotension does not occur. Although any antihypertensive medication can be used to treat these patients, the 2017 American Heart Association/American College of Cardiology (AHA/ACC), 2017 European Society of Cardiology (ESC), and 2022 Canadian guidelines favor the use of angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) as the initial choice. Importantly, data on blood pressure targets and treatment of hypertension in PAD are limited and largely stem from sub-group studies and post-hoc analysis. Large randomized trials in patients with PAD are required in the future to delineate hypertension management in this complex patient population.

Indexed as

Antihypertensive AgentsBlood PressureHypertensionPeripheral Arterial DiseaseHumansPractice Guidelines as TopicRisk FactorsTreatment OutcomeAntihypertensive Agentsangiotensin-converting enzyme inhibitorangiotensin receptor blocker.diastolic blood pressureguideline-based managementHypertensionperipheral artery diseasesystolic blood pressure

Identifiers

PMID38083897
OpenAlexW4389619235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.