Evidence map›Paper›PMID 38083883›Full record

ArticleCardiovascular & hematological agents in medicinal chemistry2024

Study of the Antihypertensive Effect of

Ayoub Amssayef, Mohammed Ajebli, Mohamed Eddouks

Abstract read
PubMed Publisher
In one paragraph

Article in Cardiovascular & hematological agents in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Plants (Basel, Switzerland) · 2025
    Review
  2. Preliminary Characterization of the Vasorelaxant Effect ofCurrent drug discovery technologies · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ayoub AmssayefTeam of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, Errachidia, BP 509 Errachidia, Morocco.
Mohammed AjebliTeam of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, Errachidia, BP 509 Errachidia, Morocco.
Mohamed EddouksTeam of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, Errachidia, BP 509 Errachidia, Morocco.
Université Moulay Ismail de Meknes · MAInstituto Superior da Maia · PT

Funding

CNRST PPR/2015/35
6 · The paper itself

Abstract

aimsThe study aimed to investigate the antihypertensive activity of

background

objectivesThis study investigated the possible antihypertensive effect of the aqueous extract of MATERIALS AND

methodsIn the present study, the antihypertensive activity of AESU was tested in normotensive and hypertensive rats Results: The results indicated that AESU decreased the systolic, diastolic, and mean arterial blood pressure in hypertensive rats. The data revealed that AESU exerted its antihypertensive effect through vasodilatory properties. Interestingly, the study demonstrated that the vasorelaxation ability of AESU might be mediated through receptor-operated calcium channels (ROCCs). However, AESU dhad effect on inhibiting ACE-2.

conclusionThe present study indicates the antihypertensive and vasorelaxant activities of AESU in hypertensive rats.

Indexed as

Antihypertensive AgentsBlood PressureHypertensionPlant ExtractsRats, WistarAnimalsMaleRatsVasodilator AgentsAntihypertensive AgentsPlant ExtractsVasodilator AgentsACE-2.aortic ringHypertensionmedicinal plantreceptor-operated calcium channelsScorzonera undulatavasodilation

Identifiers

PMID38083883
OpenAlexW4389619308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.