Evidence map›Paper›PMID 38082316›Full record

SynthesisJournal of neuroengineering and rehabilitation2023

Transcranial direct current stimulation for post-stroke dysphagia: a meta-analysis.

Nerea Gómez-García, Lorena Álvarez-Barrio, Raquel Leirós-Rodríguez, Anxela Soto-Rodríguez, Elena Andrade-Gómez, Pablo Hernández-Lucas

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Journal of neuroengineering and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 6 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07576517 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Perioperative Use of Dexmedetomidine-esketamine Combination and Transcranial Direct Current Stimulation for Prevention of Neurocognitive Complications in Older Patients After Non-cardiac Surgery: a 2×2 Factorial Trial

TypeinterventionalSponsorPeking University First HospitalRan2026 to 2030Enrolled1,160ConditionsOlder Patients, Surgery, Dexmedetomidine, EsketamineArmsDex-Esk, Placebo, Active tDCS, Sham tDCS
NCT07576543 phase4not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Long-term Follow-up of Perioperative Dexmedetomidine-esketamine Combination and Transcranial Direct Current Stimulation for Prevention of Neurocognitive Complications in Older Patients After Non-cardiac Surgery

TypeinterventionalSponsorPeking University First HospitalRan2026 to 2031Enrolled1,160ConditionsOlder Patients, Surgery, Dexmedetomidine, EsketamineArmsDex-Esk, Placebo, Active tDCS, Sham tDCS
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Effects of transcranial direct current stimulation on motor function in patients with multiple sclerosis: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
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  10. Repeated transcranial magnetic stimulation on the bilateral cerebellum to improve symptoms of ataxia with multiple system atrophy: a prospective, randomized, sham-controlled pilot study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Trial
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Risk factors for dysphagia after stroke and efficacy evaluation of swallowing function training.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  18. Article
  19. Review
  20. Therapeutic effect of proprioceptive neuromuscular facilitation combined with muscle energy technique on post-stroke dysphagia.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Nerea Gómez-GarcíaNursing and Physical Therapy Department, University of Leon, Astorga Ave., 24401, Ponferrada, Spain.
Lorena Álvarez-BarrioNursing and Physical Therapy Department, University of Leon, Astorga Ave., 24401, Ponferrada, Spain.
Raquel Leirós-RodríguezSALBIS Research Group, Nursing and Physical Therapy Department, University of Leon, Astorga Ave., 24401, Ponferrada, Spain.
Anxela Soto-RodríguezPneumology Service, Ourense Hospital, Galician Health Service, 32005, Ourense, Spain.
Elena Andrade-GómezDepartment of Nursing, University of La Rioja, La Rioja, 26004, Logroño, Spain. elena.andrade@unirioja.es.
Pablo Hernández-LucasFaculty of Physiotherapy, University of Vigo, Campus A Xunqueira, 36005, Pontevedra, Spain.
Universidad de León · ESComplejo Hospitalario de Ourense · ESUniversidad de La Rioja · ESUniversidade de Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStrokes may cause some swallowing difficulty or associated dysphagia in 25-80% of patients. This phenomenon has been linked to increased morbidity and mortality. Therefore, the aim of this study was to evaluate the efficacy of transcranial direct current stimulation in patients with dysphagia in post-stroke patients.

methodsA systematic search in PubMed, Scopus, Web of Science and MEDLINE was conducted. The articles must have to evaluate an intervention that included transcranial direct current stimulation; the sample had to consist exclusively of patients with post-stroke dysphagia; and the experimental design consisted of randomized controlled trial. Difference in mean differences and their 95% confidence interval were calculated as the between-group difference in means divided by the pooled standard deviation. The I

resultsOf the 9 investigations analyzed, all applied transcranial direct current stimulation in combination with conventional dysphagia therapy to the experimental group. All the studies analyzed identified improvements in swallowing function and meta-analysis confirmed their strong effect on reducing the risk of penetration and aspiration (Hedges's g = 0.55). The results showed that participants who received transcranial direct current stimulation significantly improved swallowing function.

conclusionsTranscranial direct current stimulation has positive effects in the treatment of poststroke dysphagia by improving swallowing function, oral and pharyngeal phase times and the risk of penetration and aspiration. Furthermore, its combination with conventional dysphagia therapy, balloon dilatation with catheter or training of the swallowing muscles ensures improvement of swallowing function. PROSPERO registration ID CRD42022314949.

Indexed as

Deglutition DisordersStrokeStroke RehabilitationTranscranial Direct Current StimulationDeglutitionHumansTreatment OutcomeCerebrovascular disordersDeglutition disordersElectric stimulationPharyngeal diseasesPhysical therapy modalitiesRehabilitation

Identifiers

PMID38082316
PMCPMC10712182
OpenAlexW4389546252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.