Evidence map›Paper›PMID 38082260›Full record

ArticleBMC public health2023

COVID-19 vaccination strategies in settings with limited rollout capacity: a mathematical modelling case study in Sierra Leone.

Gizem Mayis Bilgin, Kamalini Lokuge, Ernest Jabbie, Syarifah Liza Munira, Kathryn Glass

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Gizem Mayis BilginNational Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia. gizem.bilgin@anu.edu.au.
Kamalini LokugeNational Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia.
Ernest JabbieMinistry of Health and Sanitation, Freetown, Sierra Leone.
Syarifah Liza MuniraNational Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia.
Kathryn GlassNational Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia.
Australian National University · AUMinistry of Health and Sanitation · SL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 vaccine coverage in low- and middle-income countries continues to be challenging. As supplies increase, coverage is increasingly becoming determined by rollout capacity.

methodsWe developed a deterministic compartmental model of COVID-19 transmission to explore how age-, risk-, and dose-specific vaccine prioritisation strategies can minimise severe outcomes of COVID-19 in Sierra Leone.

resultsPrioritising booster doses to older adults and adults with comorbidities could reduce the incidence of severe disease by 23% and deaths by 34% compared to the use of these doses as primary doses for all adults. Providing a booster dose to pregnant women who present to antenatal care could prevent 38% of neonatal deaths associated with COVID-19 infection during pregnancy. The vaccination of children is not justified unless there is sufficient supply to not affect doses delivered to adults.

conclusionsOur paper supports current WHO SAGE vaccine prioritisation guidelines (released January 2022). Individuals who are at the highest risk of developing severe outcomes should be prioritised, and opportunistic vaccination strategies considered in settings with limited rollout capacity.

Indexed as

COVID-19Perinatal DeathAgedChildCOVID-19 VaccinesFemaleHumansInfant, NewbornPregnancySierra LeoneVaccinationCOVID-19 VaccinesCOVID-19Mathematical modelSARS-CoV-2VaccinationVaccine allocationVaccine prioritisation

Identifiers

PMID38082260
PMCPMC10712073
OpenAlexW4389574588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.