Evidence map›Paper›PMID 38082170›Full record

ArticleAnnals of surgical oncology2024

Clinical Effectiveness of Preoperative 18F-FDG PET/CT in Predicting Pathological Tumor Grade in Patients with Pseudomyxoma Peritonei Originating from Appendix: A Retrospective Cohort Study.

Kenta Aso, Yoshimasa Gohda, Masatoshi Hotta, Ryogo Minamimoto, Yosuke Shimizu, Yukari Uemura, Hideaki Yano

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Article in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
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  4. Imaging of Peritoneal Surface Malignancies.Journal of surgical oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kenta AsoDepartment of Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
Yoshimasa GohdaDepartment of Surgery, National Center for Global Health and Medicine, Tokyo, Japan. ygohda@hosp.ncgm.go.jp.
Masatoshi HottaDivision of Nuclear Medicine, Department of Radiology, National Center for Global Health and Medicine, Tokyo, Japan.
Ryogo MinamimotoDivision of Nuclear Medicine, Department of Radiology, National Center for Global Health and Medicine, Tokyo, Japan.
Yosuke ShimizuCenter of Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Yukari UemuraCenter of Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.
Hideaki YanoConsultant Colorectal Surgeon, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
National Center for Global Health and Medicine · JPUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

The National Center for Global Health and Medicine 21A1003
6 · The paper itself

Abstract

backgroundCytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy is the standard treatment for patients with pseudomyxoma peritonei (PMP). In some malignancies, the standard uptake value of positron emission tomography with 2-deoxy-2-18F-fluoro-D-glucose integrated with computed tomography (18F-FDG PET/CT) is now accepted as a reliable indicator of neoplastic behavior. This study aimed to evaluate the association between the maximum standardized uptake value (SUVmax) and pathological grade in patients with PMP and to investigate the significance of SUVmax in the preoperative assessment of these patients. PATIENTS AND

methodsIn this retrospective single-center study, consecutively enrolled patients diagnosed with PMP of appendiceal origin underwent preoperative 18F-FDG PET/CT. SUVmax was calculated as the highest SUVmax value in the abdomen excluding the primary site. SUVmax was compared with the pathological grade (low or high grade) of PMP tumors according to the World Health Organization classification and further analyzed with respect to the estimated cutoff point, sensitivity, specificity, and receiver operating characteristic.

resultsIn total, 160 patients were included. CRS was successfully performed in 93 patients and palliative debulking surgery in 67 patients. The pathological grade was high in 45 patients and low in 115. High-grade patients had a higher median SUVmax on 18F-FDG PET/CT than did low-grade patients (3.83 versus 2.34, p < 0.001). The highest area under the curve was 0.81, with a sensitivity of 77.8%, specificity of 72.3%, and cutoff point of 2.63.

conclusionThis study suggests that the SUVmax of preoperative 18F-FDG PET/CT is associated with the pathological grade in patients with PMP.

Indexed as

AppendixPeritoneal NeoplasmsPseudomyxoma PeritoneiFluorodeoxyglucose F18HumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesTreatment OutcomeFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID38082170
OpenAlexW4389580084

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.