Evidence map›Paper›PMID 38082147›Full record

ArticleCellular & molecular immunology2024

Oxidative stress-initiated one-carbon metabolism drives the generation of interleukin-10-producing B cells to resolve pneumonia.

Ying Fu, Baichao Yu, Qi Wang, Zhou Lu, Hushan Zhang, Dan Zhang, Feifei Luo, Ronghua Liu, Luman Wang, Yiwei Chu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular & molecular immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. A guide to B cell metabolism.Nature reviews. Immunology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. M2 macrophages promote IL-10Immunotherapy advances · 2025
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ying FuDepartment of Immunology, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Baichao YuDepartment of Immunology, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Qi WangDepartment of Immunology, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Zhou LuZhongshan Hospital Institute of Clinical Science, Zhongshan Hospital, Shanghai, China.
Hushan ZhangZhaotong Health Vocational College, Zhaotong, Yunnan, China.ORCID http://orcid.org/0000-0002-7557-4426
Dan ZhangDepartment of Immunology, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Feifei LuoDepartment of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-3834-0188
Ronghua LiuDepartment of Immunology, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Luman Wang *Department of Immunology, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China. lumanwang@fudan.edu.cn.ORCID http://orcid.org/0000-0003-0121-349X
Yiwei Chu *Department of Immunology, School of Basic Medical Sciences, Shanghai Key Laboratory of Medical Epigenetics and Metabolism, Institutes of Biomedical Sciences, Fudan University, Shanghai, China. yiweichu@fudan.edu.cn.ORCID http://orcid.org/0000-0002-5035-1111
Fudan University · CNShanghai Medical College of Fudan University · CNZhaotong University · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The metabolic reprogramming underlying the generation of regulatory B cells during infectious diseases remains unknown. Using a Pseudomonas aeruginosa-induced pneumonia model, we reported that IL-10-producing B cells (IL-10

Indexed as

Interleukin-10PneumoniaCarbonHumansInflammationOxidative StressReactive Oxygen SpeciesS-AdenosylmethionineCarbonInterleukin-10Reactive Oxygen SpeciesS-AdenosylmethionineH3K4meIL-10-producing B cellOne-carbon metabolismPneumoniaReactive oxygen species

Identifiers

PMID38082147
PMCPMC10757717
OpenAlexW4389549957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.