Evidence map›Paper›PMID 38082096›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2024

Cryoballoon ablation of atrial fibrillation in octogenarians: one year outcomes from the cryo global registry.

Dennis Lawin, Thorsten Lawrenz, K R Julian Chun, Hong-Euy Lim, Valentine Obidigbo, Jada M Selma, Peter Peytchev, Dinh Quang Nguyen, Csaba Földesi, Christoph Stellbrink and 1 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02752737 (Cryo Global Registry, a Part of the Medtronic Cardiac Ablation Post-Market Study Platform), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02752737 completednot on this map

Cryo Global Registry, a Part of the Medtronic Cardiac Ablation Post-Market Study Platform

Typeobservational_patient_registrySponsorMedtronic Cardiac Ablation SolutionsRan2016 to 2024Enrolled5,385ConditionsAtrial Fibrillation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Clinical outcomes after catheter ablation for atrial fibrillation in elderly patients: a meta-analysis with time-to-event data reconstruction.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  2. Article
  3. Long-term outcomes of catheter ablation for atrial fibrillation in octogenarians.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Observational
  4. Article
  5. Article
  6. Atrial fibrillation rhythm management: a matter of timing.European heart journal supplements : journal of the European Society of Cardiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Dennis LawinDepartment of Cardiology and Intensive Care Medicine, University Hospital OWL of Bielefeld University, Campus Klinikum Bielefeld, 50 Teutoburger Street Bielefeld, 33604, Bielefeld, Germany.ORCID http://orcid.org/0000-0002-1292-7845
Thorsten LawrenzDepartment of Cardiology and Intensive Care Medicine, University Hospital OWL of Bielefeld University, Campus Klinikum Bielefeld, 50 Teutoburger Street Bielefeld, 33604, Bielefeld, Germany.ORCID http://orcid.org/0000-0002-2930-8493
K R Julian ChunCardioangiologisches Centrum Bethanien, Frankfurt, Germany.ORCID http://orcid.org/0000-0002-2355-6015
Hong-Euy LimHallym University Sacred Heart Hospital, Anyang, Republic of Korea.ORCID http://orcid.org/0000-0001-8102-8352
Valentine ObidigboMedtronic, Inc., Minneapolis, MN, USA.
Jada M SelmaMedtronic, Inc., Minneapolis, MN, USA.ORCID http://orcid.org/0000-0003-2671-0265
Peter PeytchevOnze-Lieve-Vrouwziekenhuis, Aalst, Belgium.
Dinh Quang NguyenSt. Vinzenz-Hospital Köln, Cologne, Germany.
Csaba FöldesiGottsegen György Országos Kardiovaszkuláris Intézet, Budapest, Hungary.ORCID http://orcid.org/0000-0002-5033-117X
Christoph StellbrinkDepartment of Cardiology and Intensive Care Medicine, University Hospital OWL of Bielefeld University, Campus Klinikum Bielefeld, 50 Teutoburger Street Bielefeld, 33604, Bielefeld, Germany. christoph.stellbrink@klinikumbielefeld.de.ORCID http://orcid.org/0000-0002-8429-2826
the Cryo AF Global Registry Investigators
Bielefeld University · DEMedtronic (United States) · USCardiovascular Center Bethanien · DEGottsegen National Cardiovascular Center · HUHallym University Sacred Heart Hospital · KROnze Lieve Vrouwziekenhuis Hospital · BEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited information is available on the safety and efficacy of cryoballoon ablation (CBA) in elderly patients with atrial fibrillation (AF). Moreover, global utilization of CBA in this population (≥ 80 years old) has not been reported. This study's objectives were to determine the use, efficacy, and safety of CBA to treat octogenarians suffering from AF.

methodsIn this sub-analysis of the Cryo Global Registry, 12-month outcomes of treating AF via CBA in octogenarians were compared to patients < 80 years old. Efficacy was evaluated as time to a ≥ 30 s atrial arrhythmia (AA) recurrence. Healthcare utilization was determined via repeat ablations and hospitalizations. Improvement upon disease burden was evaluated through patient reporting of symptoms and the EQ-5D-3L quality of life (QoL) survey.

resultsThe octogenarian cohort (n = 101) had a higher prevalence of females (51.5% vs 35.7%) and CHA

conclusionsDespite more age-related comorbidities, CBA is a safe and effective treatment for AF in octogenarians, with efficacy and adverse events rates akin to ablations performed in younger patients. CLINICAL

trial registrationhttps://clinicaltrials.gov/ct2/show/NCT02752737.

Indexed as

Atrial FibrillationCryosurgeryAgedAged, 80 and overAge FactorsFemaleHumansMaleQuality of LifeRecurrenceRegistriesTreatment OutcomeAtrial fibrillationCatheter ablationCryoballoonOctogenariansRegistry

Identifiers

PMID38082096
PMCPMC11379788
OpenAlexW4389580586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.