Evidence map›Paper›PMID 38082073›Full record

ArticleThe international journal of cardiovascular imaging2024

Two-center validation of Pilot Tone based cardiac triggering of a comprehensive cardiovascular magnetic resonance examination.

Yue Pan, Juliet Varghese, Matthew S Tong, Vedat O Yildiz, Alessia Azzu, Peter Gatehouse, Rick Wage, Sonia Nielles-Vallespin, Dudley J Pennell, Ning Jin and 4 more

Open access · greenAbstract read
In one paragraph

Article in The international journal of cardiovascular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Yue PanDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Juliet VargheseDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Matthew S TongDepartment of Internal Medicine, Division of Cardiovascular Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Vedat O YildizCenter for Biostatistics, Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, OH, USA.
Alessia AzzuCardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Peter GatehouseCardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Rick WageCardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Sonia Nielles-VallespinCardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Dudley J PennellCardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Ning JinCardiovascular MR R&D, Siemens Medical Solutions USA, Malvern, PA, USA.
Mario BacherSiemens Healthineers AG, Erlangen, Germany.
Carmel HayesSiemens Healthineers AG, Erlangen, Germany.
Peter SpeierSiemens Healthineers AG, Erlangen, Germany.
Orlando P SimonettiDepartment of Biomedical Engineering, The Ohio State University, Columbus, OH, USA. Orlando.Simonetti@osumc.edu.
Royal Brompton Hospital · GBThe Ohio State University Wexner Medical Center · USSiemens Healthcare (Germany) · DESiemens Healthcare (United States) · USThe Ohio State University · US

Funding

Development and validation of cardiovascular MRI techniques on a low-field, ultra-wide bore system to assess patients with severe obesityR01HL161618 · NHLBI · OHIO STATE UNIVERSITY · PI Orlando Paul Simonetti · 2022 to 2026
$2.9M
British Heart Foundation RG/19/1/34160NHLBI NIH HHS R01 HL161618NHLBI NIH HHS R01-HL161618
6 · The paper itself

Abstract

The electrocardiogram (ECG) signal is prone to distortions from gradient and radiofrequency interference and the magnetohydrodynamic effect during cardiovascular magnetic resonance imaging (CMR). Although Pilot Tone Cardiac (PTC) triggering has the potential to overcome these limitations, effectiveness across various CMR techniques has yet to be established. To evaluate the performance of PTC triggering in a comprehensive CMR exam. Fifteen volunteers and 20 patients were recruited at two centers. ECG triggered images were collected for comparison in a subset of sequences. The PTC trigger accuracy was evaluated against ECG in cine acquisitions. Two experienced readers scored image quality in PTC-triggered cine, late gadolinium enhancement (LGE), and T1- and T2-weighted dark-blood turbo spin echo (DB-TSE) images. Quantitative cardiac function, flow, and parametric mapping values obtained using PTC and ECG triggered sequences were compared. Breath-held segmented cine used for trigger timing analysis was collected in 15 volunteers and 14 patients. PTC calibration failed in three volunteers and one patient; ECG trigger recording failed in one patient. Out of 1987 total heartbeats, three mismatched trigger PTC-ECG pairs were found. Image quality scores showed no significant difference between PTC and ECG triggering. There was no significant difference found in quantitative measurements in volunteers. In patients, the only significant difference was found in post-contrast T1 (p = 0.04). ICC showed moderate to excellent agreement in all measurements. PTC performance was equivalent to ECG in terms of triggering consistency, image quality, and quantitative image measurements across multiple CMR applications.

Indexed as

Contrast MediaGadoliniumCaffeineHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMagnetic Resonance SpectroscopyPredictive Value of TestsCaffeineContrast MediaGadoliniumCardiac triggeringCardiovascular MRIPilot ToneProspective triggering

Identifiers

PMID38082073
PMCPMC11742245
OpenAlexW4389622066

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.