ArticleEye (London, England)2024
Higher intraocular pressure is associated with slower axial growth in children with non-pathological high myopia.
Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Intraocular Pressure and Its Association with Ocular Biometrics in Children and Adolescents - 10 PLADs, China, 2020-2024.China CDC weekly · 2026Article
- Distribution of and factors associated with intraocular pressure in school-age Chinese children: findings from a large-scale longitudinal study.Eye (London, England) · 2026Article
- Associations between Intraocular Pressure or Glaucoma Medication with Axial Length and Pathologic Myopia Incidence and Progression.Ophthalmology science · 2026Article
- Association of intraocular pressure with ocular parameters in 14-18-year-old Chinese junior high students: the Anyang Childhood Eye Study.BMC ophthalmology · 2026Article
- The influence of intraocular pressure in the onset and progression of myopia in children and adolescents: a review of mechanisms and clinical significance.Frontiers in medicine · 2026Review
- Independent Effects of Axial Length and Intraocular Pressure on the Highly Myopic Optic Nerve Head.Investigative ophthalmology & visual science · 2025Article
- Bangerter filter's role in regulating ocular axial length: a novel application of an established therapy.European journal of medical research · 2025Article
- Optical and Visual Diet in Myopia.Investigative ophthalmology & visual science · 2025Review
- Intraocular pressure is a promising target for myopia control.Journal of translational medicine · 2025Article
- The correlation between intraocular pressure and choroidal microcirculation in patients with high myopia.International journal of medical sciences · 2025Observational
- Corneal Biomechanical Characteristics and Correlation Analysis in Children With Different Refractive States.Journal of ophthalmology · 2025Article
- The Mirror Theory: Parallels between Open Angle and Angle Closure Glaucoma.Life (Basel, Switzerland) · 2024Review
- Corneal biomechanics are not exclusively compromised in high myopia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
Abstract
objectivesTo investigate the association between intraocular pressure (IOP) and axial elongation rate in highly myopic children from the ZOC-BHVI High Myopia Cohort Study.
methods162 eyes of 81 healthy children (baseline spherical equivalent: -6.25 D to -15.50 D) aged 7-12 years with non-pathological high myopia were studied over five biennial visits. The mean (SD) follow-up duration was 5.2 (3.3) years. A linear mixed-effects model (LMM) was used to assess the association between IOP (at time point t-1) and axial elongation rate (annual rate of change in AL from t-1 to t), controlling for a pre-defined set of covariates including sex, age, central corneal thickness, anterior chamber depth and lens thickness (at t-1). LMM was also used to assess the contemporaneous association between IOP and axial length (AL) at t, controlling for the same set of covariates (at t) as before.
resultsHigher IOP was associated with slower axial growth (β = -0.01, 95% CI -0.02 to -0.005, p = 0.001). There was a positive contemporaneous association between IOP and AL (β = 0.03, 95% CI 0.01-0.05, p = 0.004), but this association became progressively less positive with increasing age, as indicated by a negative interaction effect between IOP and age on AL (β = -0.01, 95% CI -0.01 to -0.003, p = 0.001).
conclusionsHigher IOP is associated with slower rather than faster axial growth in children with non-pathological high myopia, an association plausibly confounded by the increased influence of ocular compliance on IOP.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.