ArticleScientific reports2023
Genome-wide characterization and evolutionary analysis of the AP2/ERF gene family in lettuce (Lactuca sativa).
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Genome-wide AP2/ERF analysis identifies HmaERF87 as a positive regulator of Hydrangea macrophylla leaf spot resistance.Plant cell reports · 2026Article
- Genome-wide identification and expression profiling of the ERF subfamily in Polygala tenuifolia seedlings under drought stress.BMC plant biology · 2026Article
- Genome-wide identification of the AP2/ERF gene family and its alternative splicing to reveal their expression profiles in different tissues of Rosa roxburghii.BMC plant biology · 2026Article
- Genome- and Transcriptome-Wide Characterization of AP2/ERF Transcription Factor Superfamily Reveals Their Relevance inPlants (Basel, Switzerland) · 2026Article
- Identification and characterization of GRAS transcription factors inFrontiers in plant science · 2026Article
- Genome-wide characterization of the AP2/ERF gene family inFrontiers in plant science · 2026Article
- Genome-wide identification and functional characterization of the DREB gene family in barley (Hordeum vulgare L.) reveal its role in drought and salinity responses.BMC genomics · 2025Article
- Integrating ATAC-Seq and Pan-Genomics Identifies Stress-MemoryFood science & nutrition · 2025Article
- Genome-wide identification and transcription profiling of safflower (Carthamus tinctorius L.) HD-ZIP gene family under water deficit.BMC genomics · 2025Article
- Genome-wide analysis of the AP2/ERF transcription factor superfamily in perennial ryegrass.BMC genomics · 2025Article
- Genome-Wide Identification of theGenes · 2025Article
- Comparative genome-wide characterization and evolutionary insights into the AP2/ERF gene family in three Coffea species (C. canephora, C. eugenioides, and C. arabica).BMC genomics · 2025Article
- Beyond the trinity: unraveling a fourth clade in the PEBP gene family in plants.Plant cell reports · 2025Article
- Genome-wide association studies in lettuce reveal the interplay of seed age, color, and germination under high temperatures.Scientific reports · 2025Article
- Genome-wide identification, structural characterization and expression profiling of AP2/ERF gene family in bayberry (Myrica rubra).BMC plant biology · 2024Article
- Identification and characterization of the Quinoa AP2/ERF gene family and their expression patterns in response to salt stress.Scientific reports · 2024Article
- Genome-wide identification and comprehensive analysis of the AP2/ERF gene family in Prunus sibirica under low-temperature stress.BMC plant biology · 2024Article
- Advance in the Thermoinhibition of Lettuce (Plants (Basel, Switzerland) · 2024Review
- Low frequency of the wild-type freezing-tolerance LsCBF7 allele among lettuce population suggests a negative selection during domestication and breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
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Authors and funding
4 authors.
Funding
Abstract
The APETALA2/ETHYLENE RESPONSIVE FACTOR (AP2/ERF) gene family plays vital roles in plants, serving as a key regulator in responses to abiotic stresses. Despite its significance, a comprehensive understanding of this family in lettuce remains incomplete. In this study, we performed a genome-wide search for the AP2/ERF family in lettuce and identified a total of 224 members. The duplication patterns provided evidence that both tandem and segmental duplications contributed to the expansion of this family. Ka/Ks ratio analysis demonstrated that, following duplication events, the genes have been subjected to purifying selection pressure, leading to selective constraints on their protein sequence. This selective pressure provides a dosage benefit against stresses in plants. Additionally, a transcriptome analysis indicated that some duplicated genes gained novel functions, emphasizing the contribution of both dosage effect and functional divergence to the family functionalities. Furthermore, an orthologous relationship study showed that 60% of genes descended from a common ancestor of Rosid and Asterid lineages, 28% from the Asterid ancestor, and 12% evolved in the lettuce lineage, suggesting lineage-specific roles in adaptive evolution. These results provide valuable insights into the evolutionary mechanisms of the AP2/ERF gene family in lettuce, with implications for enhancing abiotic stress tolerance, ultimately contributing to the genetic improvement of lettuce crop production.
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