Evidence map›Paper›PMID 38081915›Full record

ArticleCommunications biology2023

Atg7 senses ATP levels and regulates AKT

Chengsi Deng, Chunlu Li, Xiang Dong, Yang Yu, Wendong Guo, Yi Guan, Xun Sun, Liu Cao

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Chengsi DengHealth Sciences Institute, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Chunlu LiHealth Sciences Institute, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Xiang DongHealth Sciences Institute, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Yang YuHealth Sciences Institute, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Wendong GuoHealth Sciences Institute, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Yi GuanHealth Sciences Institute, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Xun SunDepartment of Immunology, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, China. wsunxun1220@cmu.edu.cn.
Liu CaoHealth Sciences Institute, College of Basic Medical Sciences, China Medical University, Shenyang, China. LCao@cmu.edu.cn.ORCID 0000-0001-6471-1993
China Medical University · CNMinistry of Education · KN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82030091
6 · The paper itself

Abstract

We report that autophagy-related gene 7 (ATG7) modulates p53 activity to regulate cell cycle and survival during metabolic stress, and that indicates Atg7 is functionally involved in cellular homeostasis in autophagy independent fashion. As a protein translation inhibitor, Programmed cell death 4 (PDCD4) expression is regulated by AKT

Indexed as

Apoptosis Regulatory ProteinsProto-Oncogene Proteins c-aktAdenosine TriphosphatePhosphorylationRNA-Binding ProteinsStress, PhysiologicalUbiquitinationAdenosine TriphosphateApoptosis Regulatory ProteinsProto-Oncogene Proteins c-aktRNA-Binding Proteins

Identifiers

PMID38081915
PMCPMC10713595
OpenAlexW4389549263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.