Evidence map›Paper›PMID 38081874›Full record

ArticleScientific reports2023

Learning exceptions to category rules varies across the menstrual cycle.

Mateja Perović, Emily M Heffernan, Gillian Einstein, Michael L Mack

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Distinct contributions of hippocampal pathways in learning regularities and exceptions revealed by functional footprints.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mateja PerovićDepartment of Psychology, University of Toronto, 100 St. George St., Toronto, ON, M5S 3J3, Canada. m.perovic@mail.utoronto.ca.ORCID 0000-0003-3865-8011
Emily M HeffernanDepartment of Psychology, University of Toronto, 100 St. George St., Toronto, ON, M5S 3J3, Canada.
Gillian EinsteinDepartment of Psychology, University of Toronto, 100 St. George St., Toronto, ON, M5S 3J3, Canada.ORCID 0000-0002-0770-5471
Michael L MackDepartment of Psychology, University of Toronto, 100 St. George St., Toronto, ON, M5S 3J3, Canada.ORCID 0000-0001-5155-7413
University of Toronto · CALinköping University · SE

Funding

Canada Foundation for Innovation and Ontario Research Fund 36601Canadian Consortium on Neurodegeneration in Aging CCNA 049-04Natural Sciences and Engineering Research Council of Canada RGPIN-2017-06753Ontario Brain Institute WJP-150643
6 · The paper itself

Abstract

Ways in which ovarian hormones affect cognition have been long overlooked despite strong evidence of their effects on the brain. To address this gap, we study performance on a rule-plus-exception category learning task, a complex task that requires careful coordination of core cognitive mechanisms, across the menstrual cycle (N = 171). Results show that the menstrual cycle distinctly affects exception learning in a manner that parallels the typical rise and fall of estradiol across the cycle. Participants in their high estradiol phase outperform participants in their low estradiol phase and demonstrate more rapid learning of exceptions than a male comparison group. A likely mechanism underlying this effect is estradiol's impact on pattern separation and completion pathways in the hippocampus. These results provide novel evidence for the effects of the menstrual cycle on category learning, and underscore the importance of considering female sex-related variables in cognitive neuroscience research.

Indexed as

Menstrual CycleProgesteroneCognitionEstradiolFemaleHumansLearningMaleEstradiolProgesterone

Identifiers

PMID38081874
PMCPMC10713535
OpenAlexW4389581057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.