Evidence map›Paper›PMID 38081744›Full record

ArticleBMJ case reports2023

Delayed healing of rectal mucosa after endoscopic submucosal dissection (ESD) with nintedanib use.

Niveditha Yalamarthi, Ali Alipouriani, Erica Savage, Emre Gorgun

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Niveditha YalamarthiDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, Ohio, USA nivedithay@hotmail.com.
Ali AlipourianiDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Erica SavageDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Emre GorgunDepartment of Colorectal Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Cleveland Clinic · USUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nintedanib is a novel antifibrotic agent used in the treatment of interstitial lung diseases. It has been associated with delayed wound healing and wound dehiscence in case reports after major surgeries when used perioperatively. This report presents an unprecedented case of a non-healing ulcer following an endorobotic submucosal dissection of a recurrent, adenomatous rectal polyp, likely due to nintedanib use. In this article, key components of the case were described with the aim to highlight a noteworthy differential diagnosis when suspecting recurrent rectal polyps as well as the need for further research on the effects of nintedanib on healing of polypectomy sites postoperatively.

Indexed as

Endoscopic Mucosal ResectionHumansIndolesMucous MembraneRectumTreatment OutcomeWound HealingIndolesnintedanibColon cancerEndoscopyGastrointestinal surgeryMalignant disease and immunosuppressionScreening (oncology)

Identifiers

PMID38081744
PMCPMC10728945
OpenAlexW4389580442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.