Evidence map›Paper›PMID 38079554›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Ring-opening metathesis polymerization of

Sarah N Hancock, Nattawut Yuntawattana, Emily Diep, Arunava Maity, An Tran, Jessica D Schiffman, Quentin Michaudel

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah N HancockDepartment of Chemistry, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-0219-2355
Nattawut YuntawattanaDepartment of Chemistry, Texas A&M University, College Station, TX 77843.
Emily DiepDepartment of Chemical Engineering, University of Massachusetts, Amherst, MA 01003.
Arunava MaityDepartment of Chemistry, Texas A&M University, College Station, TX 77843.
An TranDepartment of Chemistry, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-1377-5505
Jessica D SchiffmanDepartment of Chemical Engineering, University of Massachusetts, Amherst, MA 01003.ORCID 0000-0002-1265-5392
Quentin MichaudelDepartment of Chemistry, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-1791-9174

Funding

Primary Amines as Versatile Precursors for the Synthesis of Bioactive Molecules and Macromolecular Drug CarriersR35GM138079 · NIGMS · TEXAS A&M UNIVERSITY · PI Quentin Nicolas Michaudel · 2020 to 2026
$2.2M
NIGMS NIH HHS R35 GM138079
6 · The paper itself

Abstract

Cationic polymers have been identified as a promising type of antibacterial molecules, whose bioactivity can be tuned through structural modulation. Recent studies suggest that the placement of the cationic groups close to the core of the polymeric architecture rather than on appended side chains might improve both their bioactivity and selectivity for bacterial cells over mammalian cells. However, antibacterial main-chain cationic polymers are typically synthesized via polycondensations, which do not afford precise and uniform molecular design. Therefore, accessing main-chain cationic polymers with high degrees of molecular tunability hinges upon the development of controlled polymerizations tolerating cationic motifs (or cation progenitors) near the propagating species. Herein, we report the synthesis and ring-opening metathesis polymerization (ROMP) of

Indexed as

Methicillin-Resistant Staphylococcus aureusPolymersAnimalsAnti-Bacterial AgentsCationsHumansMammalsNorbornanesPolymerizationPyridinium Compounds1-methylpyridiniumAnti-Bacterial AgentsCationsNorbornanesPolymersPyridinium Compoundsantibacterialcationic polymerscontrolled polymerizationROMP

Identifiers

PMID38079554
PMCPMC10742381

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.