Evidence map›Paper›PMID 38078724›Full record

ArticleMicrobiology spectrum2024

The

John T Williams, Matthew Giletto, Elizabeth R Haiderer, Bilal Aleiwi, Teresa Krieger-Burke, Edmund Ellsworth, Robert B Abramovitch

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

John T WilliamsDepartment of Microbiology and Molecular Genetics, Michigan State University , East Lansing, Michigan, USA.ORCID 0000-0002-2742-1636
Matthew GilettoDepartment of Pharmacology and Toxicology, Michigan State University , East Lansing, Michigan, USA.
Elizabeth R HaidererDepartment of Microbiology and Molecular Genetics, Michigan State University , East Lansing, Michigan, USA.
Bilal AleiwiDepartment of Pharmacology and Toxicology, Michigan State University , East Lansing, Michigan, USA.
Teresa Krieger-BurkeDepartment of Pharmacology and Toxicology, Michigan State University , East Lansing, Michigan, USA.
Edmund EllsworthDepartment of Pharmacology and Toxicology, Michigan State University , East Lansing, Michigan, USA.
Robert B AbramovitchDepartment of Microbiology and Molecular Genetics, Michigan State University , East Lansing, Michigan, USA.ORCID 0000-0002-4119-4169
Michigan State University · US

Funding

Development of new M. tuberculosis MmpL3 inhibitorsR21AI148909 · NIAID · MICHIGAN STATE UNIVERSITY · PI ABRAMOVITCH, ROBERT B · 2020 to 2021
$423k
CLC NIH HHS 75N90019D00005NIAID NIH HHS R21 AI148909
6 · The paper itself

Abstract

importanceMmpL3 is a protein that is required for the survival of bacteria that cause tuberculosis (TB) and nontuberculous mycobacterial (NTM) infections. This report describes the discovery and characterization of a new small molecule, MSU-43085, that targets MmpL3 and is a potent inhibitor of

Indexed as

Mycobacterium Infections, NontuberculousMycobacterium tuberculosisTuberculosisAnimalsMiceNontuberculous Mycobacteriadrug developmentMmpL3Mycobacterium tuberculosisnontuberculous mycobacteria

Identifiers

PMID38078724
PMCPMC10783087
OpenAlexW4389558990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.