Evidence map›Paper›PMID 38078417›Full record

ArticleCell transplantation

Prion Protein Overexpression in Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Effectively Protected Rodent Kidney Against Ischemia-Reperfusion Injury Via Enhancing ATP/Mitochondrial Biogenesis-Role of ADMSC Rejuvenation and Proliferation.

Yen-Ta Chen, Chih-Chao Yang, John Y Chiang, Pei-Hsun Sung, Pei-Lin Shao, Chi-Ruei Huang, Mel S Lee, Hon-Kan Yip

Open access · goldAbstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Yen-Ta ChenDivision of Urology, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung.
Chih-Chao YangDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung.
John Y ChiangDepartment of Computer Science and Engineering, National Sun Yat-Sen University, Kaohsiung.
Pei-Hsun SungCenter for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung.
Pei-Lin ShaoDepartment of Nursing, Asia University, Taichung.
Chi-Ruei HuangCenter for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung.
Mel S LeePaochien Hospital, Pingtung.
Hon-Kan YipCenter for Shockwave Medicine and Tissue Engineering, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung.ORCID 0000-0002-6305-5717
Chang Gung University · TWAsia University · JPNational Sun Yat-sen University · TWPaochien Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe tested the hypothesis that overexpression of cellular-prion-protein in adipose-derived mesenchymal stem cells (PrPC

methodsPart I of cell culture was categorized into A1(ADMSCs)/A2(ADMSCs+p-Cresol)/A3(PrPC

resultsPart I results demonstrated that the cell viability at 24/48/72 h, BrdU uptake/number of mitDNA/APT concentration/mitochondrial-cytochrome-C+ cells and the protein expressions of ki67/PrPC at 72 h-cell culturing were significantly higher in PrPC

conclusionPrPC

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationPrionsReperfusion InjuryAdenosine TriphosphateAnimalsBiomarkersCaspase 3Cell ProliferationCresolsCytochromesInterleukin-6KidneyLipopolysaccharidesNF-kappa BOrganelle Biogenesis4-cresolAdenosine TriphosphateBiomarkersCaspase 3CresolsCytochromesInterleukin-6LipopolysaccharidesNF-kappa BPoly(ADP-ribose) Polymerase InhibitorsPrion ProteinsPrionsTumor Necrosis Factor-alphaacute kidney damageadipose tissue-derived MSCsapoptosisinflammationoverexpression of cellular proteinoxidative stress

Identifiers

PMID38078417
PMCPMC10714882
OpenAlexW4389582968

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.