Evidence map›Paper›PMID 38078003›Full record

ReviewFrontiers in cell and developmental biology2023

Sphingolipids in mitochondria-from function to disease.

Maryam Jamil, Lauren Ashley Cowart

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Local host fish-Food and waterborne parasitology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Tubulin Acetylation: A Critical Regulator of Microtubule Function.Results and problems in cell differentiation · 2025
    Review
  18. Article
  19. Role of Sphingosine-1-Phosphate Signaling Pathway in Pancreatic Diseases.International journal of molecular sciences · 2024
    Review
  20. Nutrients · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maryam JamilDepartment of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, United States.
Lauren Ashley CowartDepartment of Biochemistry and Molecular Biology, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, United States.
Virginia Commonwealth University · US

Funding

Novel sphingolipid metabolites in myocardial ischemiaR01HL151243 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI COWART, LAUREN ASHLEY · 2020 to 2024
$1.9M
Atypical sphingolipids in alcoholic liver diseaseR21AA029518 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI COWART, LAUREN ASHLEY, MONTEFUSCO, DAVID JOHN · 2023 to 2024
$438k
BLRD VA I01 BX000200BLRD VA IK6 BX006315NHLBI NIH HHS R01 HL151243NIAAA NIH HHS R21 AA029518
6 · The paper itself

Abstract

Sphingolipids are not only structural components of cellular membranes but also play vital roles in cell signaling and modulation of cellular processes. Within mitochondria, sphingolipids exert diverse effects on mitochondrial dynamics, energy metabolism, oxidative stress, and cell death pathways. In this review, we summarize literature addressing the crucial role of sphingolipids in mitochondria, highlighting their impact on mitochondrial dynamics, cellular bioenergetics, and important cell processes including apoptosis and mitophagy.

Indexed as

cancerceramidemitochondriaNAFLDS1Psphingolipids

Identifiers

PMID38078003
PMCPMC10702779
OpenAlexW4388940632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.