Evidence map›Paper›PMID 38077924›Full record

ArticleNpj viruses2023

Novel mechanism of the COVID-19 associated coagulopathy (CAC) and vascular thromboembolism.

Mahavir Singh, Sathnur Pushpakumar, Yuting Zheng, Irina Smolenkova, Oluwaseun E Akinterinwa, Bana Luulay, Suresh C Tyagi

Open access · diamondAbstract read
In one paragraph

Article in Npj viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  12. The Seraph 100Antibodies (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Mahavir SinghDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Sathnur PushpakumarDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Yuting ZhengDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Irina SmolenkovaDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Oluwaseun E AkinterinwaDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Bana LuulayDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Suresh C TyagiDepartment of Physiology, University of Louisville School of Medicine, Louisville, KY 40202, USA.
University of Louisville · US

Funding

Reversing diabetic muscle myopathy by exercise and exosomesR01HL074185 · NHLBI · UNIVERSITY OF LOUISVILLE · PI TYAGI, SURESH C. · 2003 to 2018
$5.7M
miRNA Mechanism of Acute Kidney Injury in AgingR01DK116591 · NIDDK · UNIVERSITY OF LOUISVILLE · PI SEN, UTPAL, TYAGI, SURESH C. · 2018 to 2022
$2.2M
Remote Hind Limb Ischemia Mechanism of CardioprotectionR01HL139047 · NHLBI · UNIVERSITY OF LOUISVILLE · PI TYAGI, SURESH C. · 2018 to 2021
$1.8M
Reversing Skeletal Muscle Myopathy by Hydrogen SulfideR01AR071789 · NIAMS · UNIVERSITY OF LOUISVILLE · PI TYAGI, SURESH C. · 2018 to 2023
$1.7M
NHLBI NIH HHS R01 HL074185NHLBI NIH HHS R01 HL139047NIAMS NIH HHS R01 AR071789NIDDK NIH HHS R01 DK116591
6 · The paper itself

Abstract

Previous studies from our laboratory revealed that SARS-CoV-2 spike protein (SP) administration to a genetically engineered model expressing the human angiotensin-converting enzyme 2; ACE2 receptor (i.e., hACE2 humanized mouse) mimicked the coronavirus disease-19 (COVID-19) pathology. In humans the cause of high morbidity, and mortality is due to '

Identifiers

PMID38077924
PMCPMC10710223
OpenAlexW4387741158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.