Evidence map›Paper›PMID 38077748›Full record

ArticleCrohn's & colitis 3602023

Anorectal Manometry in Patients With Fecal Incontinence After Ileal Pouch-Anal Anastomosis for Ulcerative Colitis: A Cohort Study.

Sigrid Young, Briton Lee, Scott Smukalla, Jordan Axelrad, Shannon Chang

Open access · goldAbstract read
In one paragraph

Article in Crohn's & colitis 360, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sigrid YoungDepartment of Medicine, NYU Grossman School of Medicine, New York, NY, USA.ORCID https://orcid.org/0000-0001-9673-396X
Briton LeeDepartment of Medicine, NYU Grossman School of Medicine, New York, NY, USA.
Scott SmukallaDivision of Gastroenterology, NYU Langone Health, New York, NY, USA.
Jordan AxelradDivision of Gastroenterology, Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY, USA.ORCID https://orcid.org/0000-0003-1951-7790
Shannon ChangDivision of Gastroenterology, Inflammatory Bowel Disease Center, NYU Langone Health, New York, NY, USA.ORCID https://orcid.org/0000-0001-6195-5386
NYU Langone Health · USNew York University · US

Funding

The Role of Enteric Infection in Flares of Inflammatory Bowel DiseaseK23DK124570 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AXELRAD, JORDAN ERIC · 2021 to 2025
$998k
NIDDK NIH HHS K23 DK124570
6 · The paper itself

Abstract

Background: Fecal incontinence commonly occurs in patients with ulcerative colitis and ileal pouch-anal anastomosis. There is a paucity of manometric data in pouch patients. We aimed to better define manometric parameters in pouch patients with fecal incontinence. Methods: We compared clinical and manometric variables in ulcerative colitis patients with pouch and fecal incontinence to ulcerative colitis patients with pouch without fecal incontinence and to non-ulcerative colitis patients with fecal incontinence. Manometric data for the 3 cohorts were compared to established normative data. An independent-samples Results: Among 26 pouch patients with fecal incontinence (73% female), 26 pouch patients without fecal incontinence (35% female), and 84 patients with fecal incontinence without ulcerative colitis (68% female), there were no differences in anorectal pressures between patients with fecal incontinence. Lower pressures were observed in pouch patients with fecal incontinence compared to those without fecal incontinence. Resting pressure was similar between pouch patients with fecal incontinence and healthy controls (60.9 ± 36.1 mmHg vs. 66.9 ± 3.2 mmHg, Conclusions: Pouch patients with fecal incontinence have lower anorectal pressures compared to pouch patients without incontinence, though have similar pressures to non-ulcerative colitis patients with fecal incontinence. Pouch patients with fecal incontinence have similar resting pressures as healthy controls. Distinct manometric normative values for pouch patients are needed.

Indexed as

anorectal manometryfecal incontinenceileal pouch–anal anastomosisulcerative colitis

Identifiers

PMID38077748
PMCPMC10708921
OpenAlexW4387805264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.