Evidence map›Paper›PMID 38077092›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in

Pradeep S Chauhan, Irfan Alahi, Savar Sinha, Alexander L Shiang, Ryan Mueller, Jace Webster, Ha X Dang, Debanjan Saha, Lilli Greiner, Breanna Yang and 13 more

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 1 country.

Pradeep S ChauhanORCID 0000-0003-4304-011X
Alexander L Shiang
Ryan Mueller
Ha X Dang
Debanjan Saha
Lilli Greiner
Breanna Yang
Gabris Ni
Elisa M Ledet
Ramandeep K Babbra
Wenjia Feng
Peter K Harris
Faridi Qaium
Ellen B Jaeger
Patrick J Miller
Sydney A Caputo
Russell K Pachynski
Christopher A Maher
Aadel A ChaudhuriORCID 0000-0003-3115-3061
Washington University in St. Louis · USTulane University · USJames S. McDonnell Foundation · USMayo Clinic · USUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic castration-resistant prostate cancer (mCRPC) resistant to androgen receptor (AR)-targeted agents is often lethal. Unfortunately, biomarkers for this deadly disease remain under investigation, and underpinning mechanisms are ill-understood. Here, we applied deep sequencing to ∼100 mCRPC patients prior to the initiation of first-line AR-targeted therapy, which detected

Identifiers

PMID38077092
PMCPMC10705653
OpenAlexW4389273015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.