Evidence map›Paper›PMID 38077034›Full record

ArticlebioRxiv : the preprint server for biology2023

Profiling Expression Strategies for a Type III Polyketide Synthase in a Lysate-Based, Cell-free System.

Tien T Sword, Jaime Lorenzo N Dinglasan, Ghaeath S K Abbas, J William Barker, Madeline E Spradley, Elijah R Greene, Damian S Gooden, Scott J Emrich, Michael A Gilchrist, Mitchel J Doktycz and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Tien T SwordDepartment of Chemistry, University of Tennessee-Knoxville (Knoxville, TN USA).
Jaime Lorenzo N DinglasanBiosciences Division, Oak Ridge National Laboratory (Oak Ridge, TN USA).ORCID 0000-0002-4584-5045
Ghaeath S K AbbasDepartment of Chemistry, University of Tennessee-Knoxville (Knoxville, TN USA).
J William BarkerDepartment of Chemistry, University of Tennessee-Knoxville (Knoxville, TN USA).
Madeline E SpradleyDepartment of Biochemistry, Cellular, and Molecular Biology, University of Tennessee-Knoxville (Knoxville, TN USA).
Elijah R GreeneDepartment of Chemistry, University of Tennessee-Knoxville (Knoxville, TN USA).
Damian S GoodenDepartment of Chemistry, University of Tennessee-Knoxville (Knoxville, TN USA).
Scott J EmrichGraduate School of Genome Science & Technology, University of Tennessee-Knoxville Knoxville (Knoxville, TN USA).ORCID 0000-0002-5741-4517
Michael A GilchristGraduate School of Genome Science & Technology, University of Tennessee-Knoxville Knoxville (Knoxville, TN USA).
Mitchel J DoktyczBiosciences Division, Oak Ridge National Laboratory (Oak Ridge, TN USA).ORCID 0000-0003-4856-8343
Constance B BaileyDepartment of Chemistry, University of Tennessee-Knoxville (Knoxville, TN USA).ORCID 0000-0002-4668-7245
Knoxville College · USOak Ridge National Laboratory · USThe University of Sydney · AU

Funding

The BioGradMatch ProgramR41GM145182 · NIGMS · ADMIT ACADEMY LLC · PI JOSH, LEVINE, WARRICK, CYNTHIA A · 2022 to 2022
$150k
NIGMS NIH HHS R41 GM145182
6 · The paper itself

Abstract

Some of the most metabolically diverse species of bacteria (e.g., Actinobacteria) have higher GC content in their DNA, differ substantially in codon usage, and have distinct protein folding environments compared to tractable expression hosts like

Identifiers

PMID38077034
PMCPMC10705458
OpenAlexW4389257786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.