Evidence map›Paper›PMID 38077028›Full record

ArticlebioRxiv : the preprint server for biology2024

copepodTCR: Identification of Antigen-Specific T Cell Receptors with combinatorial peptide pooling.

Vasilisa A Kovaleva, David J Pattinson, Carl Barton, Sarah R Chapin, Anastasia A Minervina, Katherine A Richards, Andrea J Sant, Paul G Thomas, Mikhail V Pogorelyy, Hannah V Meyer

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Vasilisa A KovalevaSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.ORCID 0000-0003-0215-4938
David J PattinsonDepartment of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53711, USA.ORCID 0000-0003-0001-8203
Carl BartonBirkbeck, University of London, WC1E 7HX London, UK.ORCID 0000-0001-6938-9446
Sarah R ChapinSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.ORCID 0000-0002-7775-3380
Anastasia A MinervinaDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Katherine A RichardsDavid H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Andrea J SantDavid H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Paul G ThomasDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0001-7955-0256
Mikhail V PogorelyyDepartment of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0003-0773-1204
Hannah V MeyerSimons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.ORCID 0000-0003-4564-0899
St. Jude Children's Research Hospital · USCold Spring Harbor Laboratory · USBirkbeck, University of London · GBUniversity of Rochester Medical Center · USUniversity of Wisconsin–Madison · US

Funding

DECODING THE INTERACTIONS BETWEEN T CELL RECEPTORS AND PEPTIDE-MHCR01AI136514 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Paul G. Thomas · 2018 to 2026
$6.9M
DYNAMICS AND EVOLUTION OF IMMUNE RESPONSES TO INFLUENZA VIRUSESU01AI150747 · NIAID · EMORY UNIVERSITY · PI AHMED, RAFI, ANTIA, RUSTOM NOSHIR · 2020 to 2024
$5.9M
Dissecting dynamic genetic effects from thymus development to immune-mediated diseaseR01AI167862 · NIAID · COLD SPRING HARBOR LABORATORY · PI Hannah Verena Meyer · 2022 to 2026
$2.5M
Graphical Processing Units and a Large-Memory Compute Node for Applications in Genomics, Neuroscience, and Structural BiologyS10OD028632 · OD · COLD SPRING HARBOR LABORATORY · PI SIEPEL, ADAM CHARLES · 2020 to 2020
$437k
NIAID NIH HHS R01 AI136514NIAID NIH HHS R01 AI167862NIAID NIH HHS U01 AI150747NIH HHS S10 OD028632
6 · The paper itself

Abstract

T cell receptor (TCR) repertoire diversity enables the orchestration of antigen-specific immune responses against the vast space of possible pathogens. Identifying TCR/antigen binding pairs from the large TCR repertoire and antigen space is crucial for biomedical research. Here, we introduce

Identifiers

PMID38077028
PMCPMC10705480
OpenAlexW4389117504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.