Evidence map›Paper›PMID 38076927›Full record

ArticlebioRxiv : the preprint server for biology2023

Multicellular magnetotactic bacterial consortia are metabolically differentiated and not clonal.

George A Schaible, Zackary J Jay, John Cliff, Frederik Schulz, Colin Gauvin, Danielle Goudeau, Rex R Malmstrom, S Emil Ruff, Virginia Edgcomb, Roland Hatzenpichler

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

George A SchaibleDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0002-1031-4682
Zackary J JayDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0003-3062-4933
John CliffEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA 99354.ORCID 0000-0002-7395-5604
Frederik SchulzDepartment of Energy Joint Genome Institute, Berkeley, CA, 94720.ORCID 0000-0002-4932-4677
Colin GauvinCenter for Biofilm Engineering, Montana State University, Bozeman, MT 59717.ORCID 0000-0001-7171-552X
Danielle GoudeauDepartment of Energy Joint Genome Institute, Berkeley, CA, 94720.ORCID 0000-0002-3785-032X
Rex R MalmstromDepartment of Energy Joint Genome Institute, Berkeley, CA, 94720.ORCID 0000-0002-4758-7369
S Emil RuffEcosystems Center and Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA, 02543.ORCID 0000-0002-6872-6188
Virginia EdgcombWoods Hole Oceanographic Institution, Falmouth, MA 02543.ORCID 0000-0001-6805-381X
Roland HatzenpichlerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717.ORCID 0000-0002-5489-3444
Montana State University · USJoint Genome Institute · USMarine Biological Laboratory · USPacific Northwest National Laboratory · USWoods Hole Oceanographic Institution · US

Funding

Surveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP30GM140963 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2021 to 2025
$6.9M
NIGMS NIH HHS P30 GM140963
6 · The paper itself

Abstract

Consortia of multicellular magnetotactic bacteria (MMB) are currently the only known example of bacteria without a unicellular stage in their life cycle. Because of their recalcitrance to cultivation, most previous studies of MMB have been limited to microscopic observations. To study the biology of these unique organisms in more detail, we use multiple culture-independent approaches to analyze the genomics and physiology of MMB consortia at single cell resolution. We separately sequenced the metagenomes of 22 individual MMB consortia, representing eight new species, and quantified the genetic diversity within each MMB consortium. This revealed that, counter to conventional views, cells within MMB consortia are not clonal. Single consortia metagenomes were then used to reconstruct the species-specific metabolic potential and infer the physiological capabilities of MMB. To validate genomic predictions, we performed stable isotope probing (SIP) experiments and interrogated MMB consortia using fluorescence

Identifiers

PMID38076927
PMCPMC10705294
OpenAlexW4389069301

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.