Evidence map›Paper›PMID 38076858›Full record

ArticlebioRxiv : the preprint server for biology2023

Unlocking the Role of sMyBP-C: A Key Player in Skeletal Muscle Development and Growth.

Taejeong Song, James W McNamara, Akhil Baby, Weikang Ma, Maicon Landim-Vieira, Sankar Natesan, Jose Renato Pinto, John N Lorenz, Thomas C Irving, Sakthivel Sadayappan

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Taejeong SongCenter for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.ORCID 0000-0001-6648-1263
James W McNamaraCenter for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.ORCID 0000-0003-3754-6405
Akhil BabyCenter for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
Weikang MaBioCAT, Department of Biology, Illinois Institute of Technology, Chicago, IL, USA.ORCID 0000-0001-9535-7114
Maicon Landim-VieiraDepartment of Biomedical Sciences, Florida State University, Tallahassee, FL, USA.
Sankar NatesanDepartment of Genetic Engineering, School of Biotechnology, Madurai Kamaraj University, Madurai, India.
Jose Renato PintoDepartment of Biomedical Sciences, Florida State University, Tallahassee, FL, USA.
John N LorenzDepartment of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Thomas C IrvingBioCAT, Department of Biology, Illinois Institute of Technology, Chicago, IL, USA.
Sakthivel SadayappanCenter for Cardiovascular Research, Division of Cardiovascular Health and Disease, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.ORCID 0000-0003-2006-7678
University of Cincinnati · USFlorida State University · USIllinois Institute of Technology · USMadurai Kamaraj University · INUniversity of Cincinnati Medical Center · US

Funding

The Biophysics Collaborative Access Team (User Training and Outreach)P30GM138395 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI THOMAS C IRVING · 2021 to 2026
$16.5M
Fast myosin binding protein-C and cardiac contractility in heart failureR01HL105826 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2011 to 2025
$4.5M
Skeletal muscle sarcomere function in health and diseaseR01AR079477 · NIAMS · UNIVERSITY OF MINNESOTA · PI JOSEPH Mark METZGER · 2022 to 2026
$2.6M
Skeletal Myosin-Binding Protein C Regulation and Structural DynamicsR01AR079435 · NIAMS · UNIVERSITY OF ARIZONA · PI Brett A Colson · 2022 to 2026
$2.4M
The mechanisms of cardiac thin filament regulation in health and disease.R01HL160966 · NHLBI · OLD DOMINION UNIVERSITY · PI CHASE, P. BRYANT, GALKIN, VITOLD · 2022 to 2025
$2.3M
Slow myosin binding protein-C in skeletal muscle physiologyR01AR078001 · NIAMS · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2020 to 2023
$1.8M
Molecular mechanism of hypertrophic cardiomyopathy in populations of South Asian descendantsR01HL130356 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2016 to 2019
$1.6M
Isolation, Characterization and Reconstruction of Vertebrate Striated Muscle Myosin FilamentsR21AR077802 · NIAMS · FLORIDA STATE UNIVERSITY · PI PINTO, JOSE RENATO, TAYLOR, KENNETH ALLEN · 2020 to 2021
$356k
NHLBI NIH HHS R01 HL105826NHLBI NIH HHS R01 HL130356NHLBI NIH HHS R01 HL160966NIAMS NIH HHS R01 AR078001NIAMS NIH HHS R01 AR079435NIAMS NIH HHS R01 AR079477NIAMS NIH HHS R21 AR077802NIGMS NIH HHS P30 GM138395
6 · The paper itself

Abstract

Skeletal muscle is the largest organ in the body, responsible for gross movement and metabolic regulation. Recently, variants in the

Identifiers

PMID38076858
PMCPMC10705270
OpenAlexW4388266472

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.