Evidence map›Paper›PMID 38076798›Full record

ArticleResearch square2023

The Effect of Race and Area Deprivation on Symptom Profiles over the Course of Early-Stage Breast Cancer.

Hiba Abujaradeh, Julia O'Brien, Susan R Mazanec, Catherine M Bender, Isabelle M Schlemmer, Adam M Brufsky, Elham Nasrollahi, Margaret Rosenzweig

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hiba AbujaradehUniversity of Pittsburgh.
Julia O'BrienUniversity of Pittsburgh.
Susan R MazanecCase Western Reserve University.
Catherine M BenderUniversity of Pittsburgh.
Isabelle M SchlemmerUniversity of Pittsburgh.
Adam M BrufskyUPMC Hillman Cancer Center.
Elham NasrollahiUPMC Hillman Cancer Center.
Margaret RosenzweigUniversity of Pittsburgh.
University of Pittsburgh · USUPMC Hillman Cancer Center · USCase Western Reserve University · US

Funding

The Symptom Experience, Management and Outcomes According to Race and Social Determinants of Health (SEMOARS) during Breast Cancer ChemotherapyR01MD012245 · NIMHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROSENZWEIG, MARGARET Q. · 2017 to 2021
$3.3M
NIMHD NIH HHS R01 MD012245
6 · The paper itself

Abstract

Purpose: This study compared common symptoms (fatigue, pain), overall physical functioning and changes over time between Black and White women receiving early-stage breast cancer (ESBC) chemotherapy. Methods: A longitudinal, repeated measures comparative design was employed. Time points of symptom measurement (PROMIS domains) at baseline, mid and end point were adjusted as per patient chemotherapy schedule. Analyses: Linear mixed models were applied. Results: There were 147 patients, 36% Black 64% White (54±12 years) recommended to receive early-stage breast cancer chemotherapy with adequate data for symptom analysis. Pain: Main effect of race was significant ( Fatigue: Fatigue significantly increased (deteriorated) at endpoint (MD Conclusion: Symptom burden significantly increased over the course of chemotherapy for all patients. Scores for pain and physical function were higher overall for Black patients and deteriorated at a greater rate for Black vs. White women over the course of chemotherapy. This assessment holds implication for proactive assessment and mitigation strategies.

Indexed as

breast cancerracial disparitiessymptom burden

Identifiers

PMID38076798
PMCPMC10705700
OpenAlexW4389088560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.