Evidence map›Paper›PMID 38076565›Full record

ArticleFrontiers in veterinary science2023

Isolation, characterization, and immunomodulatory activity evaluation of probiotic strains from colostrum and canine milk.

Sandra Rayén Quilodrán-Vega, Carolina Muñoz-Flores, Ana Pino, Paula Buldres, Felipe Sandoval, Alex Aguirre, Brígida Portillo, Natalie Parra, Claudia Altamirano, Leonardo Albarracín and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Sandra Rayén Quilodrán-VegaLaboratory of Food Microbiology, Faculty of Veterinary Sciences, Universidad de Concepción, Chillán, Chile.
Carolina Muñoz-FloresLaboratory of Food Microbiology, Faculty of Veterinary Sciences, Universidad de Concepción, Chillán, Chile.
Ana PinoLaboratory of Food Microbiology, Faculty of Veterinary Sciences, Universidad de Concepción, Chillán, Chile.
Paula BuldresBiotechnology and Biopharmaceuticals Laboratory, Departamento de Fisiopatología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Felipe SandovalBiotechnology and Biopharmaceuticals Laboratory, Departamento de Fisiopatología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Alex AguirreLaboratory of Food Microbiology, Faculty of Veterinary Sciences, Universidad de Concepción, Chillán, Chile.
Brígida PortilloLaboratory of Food Microbiology, Faculty of Veterinary Sciences, Universidad de Concepción, Chillán, Chile.
Natalie ParraBiotechnology and Biopharmaceuticals Laboratory, Departamento de Fisiopatología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
Claudia AltamiranoLaboratorio de Cultivos Celulares, Escuela de Ingeniería Bioquímica, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Leonardo AlbarracínLaboratory of Immunobiotechnology, Reference Centre for Lactobacilli (CERELA-CONICET), San Miguel de Tucumán, Argentina.
Julio VillenaLaboratory of Immunobiotechnology, Reference Centre for Lactobacilli (CERELA-CONICET), San Miguel de Tucumán, Argentina.
Jorge R ToledoBiotechnology and Biopharmaceuticals Laboratory, Departamento de Fisiopatología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.
University of Concepción · CLConsejo Nacional de Investigaciones Científicas y Técnicas · ARPontificia Universidad Católica de Valparaíso · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to characterize potential probiotic strains for use in dogs to prevent infectious enteropathies. Lactic acid bacteria (LAB) isolated from canine milk and colostrum were characterized according to their functional properties, including their resistance to gastrointestinal conditions, inhibitory effect against pathogens, and intestinal adhesion. Methods: The immunomodulatory effects of the strains were also analyzed in Results: The TUCO-16 and TUCO-17 strains induced a significant increase in the expression of TNF-α, IL-8, and TLR2 in canine macrophages. The oral administration of TUCO-16 and TUCO-17 strains to mice significantly augmented their resistance to pathogenic Conclusion: Both strains, TUCO-16 and TUCO-17, are potential probiotic candidates for improving intestinal health in dogs, particularly for their ability to inhibit the growth of Gram-negative pathogens common in gastrointestinal infections and modulate the animal's immune response. Further studies are required to effectively demonstrate the beneficial effects of TUCO-16 and TUCO-17 strains in dogs.

Indexed as

doggastrointestinal infectionimmunomodulatory lactic acid bacteriamilk strainsprobiotic

Identifiers

PMID38076565
PMCPMC10701529
OpenAlexW4388945377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.