Evidence map›Paper›PMID 38076464›Full record

ReviewFrontiers in cellular and infection microbiology2023

Flying under the radar - impact and factors influencing asymptomatic DENV infections.

Paulo Henriques, Alexandra Rosa, Helena Caldeira-Araújo, Pedro Soares, Ana Margarida Vigário

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Mouse models as a tool to study asymptomatic DENV infections.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Paulo HenriquesProjecto Medicina, Faculdade de Ciências da Vida, Universidade da Madeira, Funchal, Portugal.
Alexandra RosaProjecto Medicina, Faculdade de Ciências da Vida, Universidade da Madeira, Funchal, Portugal.
Helena Caldeira-AraújoProjecto Medicina, Faculdade de Ciências da Vida, Universidade da Madeira, Funchal, Portugal.
Pedro SoaresDepartment of Biology, CBMA (Centre of Molecular and Environmental Biology), Braga, Portugal.
Ana Margarida VigárioProjecto Medicina, Faculdade de Ciências da Vida, Universidade da Madeira, Funchal, Portugal.
Universidade da Madeira · PTUniversity of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical outcome of DENV and other Flaviviruses infections represents a spectrum of severity that ranges from mild manifestations to severe disease, which can ultimately lead to death. Nonetheless, most of these infections result in an asymptomatic outcome that may play an important role in the persistent circulation of these viruses. Also, although little is known about the mechanisms that lead to these asymptomatic infections, they are likely the result of a complex interplay between viral and host factors. Specific characteristics of the infecting viral strain, such as its replicating efficiency, coupled with host factors, like gene expression of key molecules involved in the immune response or in the protection against disease, are among crucial factors to study. This review revisits recent data on factors that may contribute to the asymptomatic outcome of the world's widespread DENV, highlighting the importance of silent infections in the transmission of this pathogen and the immune status of the host.

Indexed as

DengueDengue VirusFlavivirusFlavivirus InfectionsAsymptomatic InfectionsHumansasymptomatic infectionsdengueDENV infectionflavivirus infectionshost factors

Identifiers

PMID38076464
PMCPMC10704250
OpenAlexW4388974780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.