Evidence map›Paper›PMID 38076276›Full record

ArticleFrontiers in medicine2023

Comparisons of the clinical outcomes of Centurion

Yinan Liu, Jing Hong, Xiaoyong Chen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07222150 (Unity VCS), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07222150 narecruitingnot on this mapstarted 2025, after this paper: background citation

Unity VCS: A Comparison Study Evaluating Corneal Clarity and Thickness at Day 1 and Day 8 Post Op

TypeinterventionalSponsorMetrolina Eye Associates, PLLCRan2025 to 2026Enrolled105ConditionsCataractArmsCataract surgery with Unity VCS, Cataract surgery with Centurion with Ozil
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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  14. EVA NEXUS-Phaco performance study.International journal of ophthalmology · 2024
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yinan LiuDepartment of Ophthalmology, Peking University Third Hospital, Beijing, China.
Jing HongDepartment of Ophthalmology, Peking University Third Hospital, Beijing, China.
Xiaoyong ChenDepartment of Ophthalmology, Peking University Third Hospital, Beijing, China.
Peking University Third Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: During cataract phacoemulsification surgery, the Alcon Centurion with Active Sentry can achieve a more stable anterior chamber, which allows a lower intraocular pressure (IOP) setting than the gravity fluidics system. In this randomized controlled trial, we compared these two systems' damage to the cornea under different IOP settings. Methods: Seventy-eight eyes of 53 patients with corneal endothelial cell density (ECD) of 500∼1500/mm Results: We observed no significant differences in best corrected visual acuity (BCVA), cumulative dissipated energy (CDE), total case time, estimated fluidics usage (EFU) and ophthalmic viscoelastic devices (OVDs) usage between the two groups. The enrolled eyes were further divided into soft nucleus (27 eyes) and hard nucleus (51 eyes) subgroups. And we found less pain complaint during surgeries, lower corneal edema ratio at 1-day and 1-week visit, smaller CCT changes at 1-day visit and lower ECD loss rate at 1-month visit ( Conclusion: Owing to a lower IOP setting, Centurion Clinical Trial Registration: https://www.chictr.org.cn, identifier ChiCTR2300077865.

Indexed as

Active SentryAlcon Centurion®corneal edemacorneal endothelial cell densityphacoemulsification

Identifiers

PMID38076276
PMCPMC10704024
OpenAlexW4389006054

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.