Evidence map›Paper›PMID 38076186›Full record

ArticleHeliyon2023

Antioxidant, carbonic anhydrase inhibition and diuretic activity of

Noreena Masood, QurratUlAin Jamil, Muhammad Irfan Aslam, Muhammad Irfan Masood, Jafir Hussain Shirazi, Qazi Adnan Jamil, Muhammad Saeed Jan, Bader Alsuwayt, Ashfaq Ahmad, Sulaiman Mohammed Abdullah Alnasser and 2 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Exploring the Therapeutic Potential ofFood science & nutrition · 2026
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  3. Pharmaceuticals (Basel, Switzerland) · 2025
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  6. Cardioprotective effects ofFrontiers in pharmacology · 2025
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  9. Exploration of the anti-inflammatory potential ofFrontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Noreena MasoodDepartment of Pharmacology, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
QurratUlAin JamilDepartment of Pharmacy Practice, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Muhammad Irfan AslamDepartment of Pharmacology, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Muhammad Irfan MasoodInstitute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
Jafir Hussain ShiraziDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Qazi Adnan JamilDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Muhammad Saeed JanDepartment of Pharmacy, Bacha Khan University, Charsadda 24420, Pakistan.
Bader AlsuwaytDepartment of Pharmacy Practice, College of Pharmacy, University of Hafr Al batin, Hafr Al batin 39524, Saudi Arabia.
Ashfaq AhmadDepartment of Pharmacy Practice, College of Pharmacy, University of Hafr Al batin, Hafr Al batin 39524, Saudi Arabia.
Sulaiman Mohammed Abdullah AlnasserDepartment of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim University, Qassim 51452, Saudi Arabia.
Mohammed AufyDivision of Pharmacology and Toxicology, University of Vienna, UZA II, Josef-Holaubek-Platz 2, A-1090, Vienna, Austria.
Shahid Muhammad IqbalDepartment of Pharmacology, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Islamia University of Bahawalpur · PKUniversity of Hafr Al-Batin · SABacha Khan University · PKQassim University · SAUniversity of Veterinary and Animal Sciences · PKUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The 70 % methanolic Results: Lp.Cr. indicated high phenolic and flavonoid contents which correlated with good antioxidant activity. GC-MS analysis showed the presence of 104 compounds from different phytochemical classes. Diuretic activity was performed at 10-300 mg/kg concentrations where the dose of 100 and 300 mg/kg showed good diuretic and saluretic activity comparable to furosemide. Lp.Cr exhibited diuresis both in acute and prolonged study protocols which can be attributed to carbonic anhydrase inhibition, effect on prostaglandins and cholinergic pathways. Conclusion:

Indexed as

AntioxidantCarbonic anhydraseDiureticGC-MSLeptadenia pyrotechnicaSaluretic

Identifiers

PMID38076186
PMCPMC10709400
OpenAlexW4388764648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.